Detalhe da pesquisa
1.
SIKs Regulate HDAC7 Stabilization and Cytokine Recall in Late-Stage T Cell Effector Differentiation.
J Immunol
; 211(12): 1767-1782, 2023 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37947442
2.
The preferential transport of NO3- by full-length Guillardia theta anion channelrhodopsin 1 is enhanced by its extended cytoplasmic domain.
J Biol Chem
; 299(11): 105305, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37778732
3.
Multistep conformational changes leading to the gate opening of light-driven sodium pump rhodopsin.
J Biol Chem
; 299(12): 105393, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37890784
4.
Development of a high-throughput dual-stream liquid chromatography-tandem mass spectrometry method to screen for inhibitors of glutamate carboxypeptidase II.
Rapid Commun Mass Spectrom
; : e9772, 2024 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38867136
5.
Real-time identification of two substrate-binding intermediates for the light-driven sodium pump rhodopsin.
J Biol Chem
; 296: 100792, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34019877
6.
Model studies towards prodrugs of the glutamine antagonist 6-diazo-5-oxo-l-norleucine (DON) containing a diazo precursor.
Bioorg Med Chem Lett
; 50: 128321, 2021 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34400301
7.
Spectroscopic Characterization of Halorhodopsin Reconstituted into Nanodisks Using Native Lipids.
Biophys J
; 118(11): 2853-2865, 2020 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32396848
8.
Direct Detection of the Substrate Uptake and Release Reactions of the Light-Driven Sodium-Pump Rhodopsin.
J Am Chem Soc
; 142(37): 16023-16030, 2020 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32844642
9.
Methodology for Further Thermostabilization of an Intrinsically Thermostable Membrane Protein Using Amino Acid Mutations with Its Original Function Being Retained.
J Chem Inf Model
; 60(3): 1709-1716, 2020 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32155058
10.
Allosteric kidney-type glutaminase (GLS) inhibitors with a mercaptoethyl linker.
Bioorg Med Chem
; 28(20): 115698, 2020 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33069080
11.
Upregulation of the Glutaminase II Pathway Contributes to Glutamate Production upon Glutaminase 1 Inhibition in Pancreatic Cancer.
Proteomics
; 19(21-22): e1800451, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31231915
12.
Structural and computational basis for potent inhibition of glutamate carboxypeptidase II by carbamate-based inhibitors.
Bioorg Med Chem
; 27(2): 255-264, 2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30552009
13.
Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer.
Proc Natl Acad Sci U S A
; 113(36): E5328-36, 2016 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27559084
14.
Spectroscopic characteristics of Rubricoccus marinus xenorhodopsin (RmXeR) and a putative model for its inward H+ transport mechanism.
Phys Chem Chem Phys
; 20(5): 3172-3183, 2018 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-29034950
15.
X-ray Crystallographic Structure of Thermophilic Rhodopsin: IMPLICATIONS FOR HIGH THERMAL STABILITY AND OPTOGENETIC FUNCTION.
J Biol Chem
; 291(23): 12223-32, 2016 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27129243
16.
Demonstration of a Light-Driven SO42- Transporter and Its Spectroscopic Characteristics.
J Am Chem Soc
; 139(12): 4376-4389, 2017 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28257611
17.
Probing the Cl--pumping photocycle of pharaonis halorhodopsin: Examinations with bacterioruberin, an intrinsic dye, and membrane potential-induced modulation of the photocycle.
Biochim Biophys Acta
; 1847(8): 748-58, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25960108
18.
D-Amino acid oxidase inhibitors based on the 5-hydroxy-1,2,4-triazin-6(1H)-one scaffold.
Bioorg Med Chem Lett
; 26(8): 2088-91, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26965861
19.
Molecular and evolutionary aspects of microbial sensory rhodopsins.
Biochim Biophys Acta
; 1837(5): 562-77, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23732219
20.
Converting a light-driven proton pump into a light-gated proton channel.
J Am Chem Soc
; 137(9): 3291-9, 2015 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25712566