Detalhe da pesquisa
1.
Radiosynthesis and evaluation of a fluorine-18 radiotracer [18F]FS1P1 for imaging sphingosine-1-phosphate receptor 1.
Org Biomol Chem
; 20(5): 1041-1052, 2022 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35029272
2.
PET Study of Sphingosine-1-phosphate Receptor 1 Expression in Response to S. aureus Infection.
Mol Imaging
; 2021: 9982020, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34934406
3.
Spatially constrained kinetic modeling with dual reference tissues improves 18F-flortaucipir PET in studies of Alzheimer disease.
Eur J Nucl Med Mol Imaging
; 48(10): 3172-3186, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33599811
4.
Pyrazole Scaffold Synthesis, Functionalization, and Applications in Alzheimer's Disease and Parkinson's Disease Treatment (2011-2020).
Molecules
; 26(5)2021 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33668128
5.
Synthesis and in vitro evaluation of new TRPV4 ligands and biodistribution study of an 11C-labeled radiotracer in rodents.
Bioorg Med Chem Lett
; 30(22): 127573, 2020 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32980513
6.
Development of a carbon-11 PET radiotracer for imaging TRPC5 in the brain.
Org Biomol Chem
; 17(22): 5586-5594, 2019 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31115430
7.
Design, synthesis, and in vitro bioactivity evaluation of fluorine-containing analogues for sphingosine-1-phosphate 2 receptor.
Bioorg Med Chem
; 27(16): 3619-3631, 2019 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31279524
8.
Kinetic modeling of [18 F]VAT, a novel radioligand for positron emission tomography imaging vesicular acetylcholine transporter in non-human primate brain.
J Neurochem
; 144(6): 791-804, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29315563
9.
C. Elegans Fatty Acid Two-Hydroxylase Regulates Intestinal Homeostasis by Affecting Heptadecenoic Acid Production.
Cell Physiol Biochem
; 49(3): 947-960, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30184537
10.
Design and synthesis of pyrazolopyridine derivatives as sphingosine 1-phosphate receptor 2 ligands.
Bioorg Med Chem Lett
; 28(3): 488-496, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29249563
11.
Radiosynthesis and evaluation of a fluorine-18 labeled radioligand targeting vesicular acetylcholine transporter.
Bioorg Med Chem Lett
; 28(21): 3425-3430, 2018 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30274694
12.
Design, synthesis, and in vitro evaluation of quinolinyl analogues for α-synuclein aggregation.
Bioorg Med Chem Lett
; 28(6): 1011-1019, 2018 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29482941
13.
Syntheses and in vitro biological evaluation of S1PR1 ligands and PET studies of four F-18 labeled radiotracers in the brain of nonhuman primates.
Org Biomol Chem
; 16(47): 9171-9184, 2018 12 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30462126
14.
PET Study of Sphingosine-1-Phosphate Receptor 1 Expression in Response to Vascular Inflammation in a Rat Model of Carotid Injury.
Mol Imaging
; 16: 1536012116689770, 2017 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28654378
15.
A promising carbon-11-labeled sphingosine-1-phosphate receptor 1-specific PET tracer for imaging vascular injury.
J Nucl Cardiol
; 24(2): 558-570, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26843200
16.
Synthesis, resolution, and in vitro evaluation of three vesicular acetylcholine transporter ligands and evaluation of the lead fluorine-18 radioligand in a nonhuman primate.
Org Biomol Chem
; 15(24): 5197-5209, 2017 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28590490
17.
Chiral resolution of serial potent and selective σ1 ligands and biological evaluation of (-)-[18F]TZ3108 in rodent and the nonhuman primate brain.
Bioorg Med Chem
; 25(4): 1533-1542, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28129990
18.
Preclinical evaluation of a promising C-11 labeled PET tracer for imaging phosphodiesterase 10A in the brain of living subject.
Neuroimage
; 121: 253-62, 2015 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26216275
19.
Synthesis and in vitro characterization of cinnoline and benzimidazole analogues as phosphodiesterase 10A inhibitors.
Bioorg Med Chem Lett
; 25(4): 919-24, 2015 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25592707
20.
A potent and selective C-11 labeled PET tracer for imaging sphingosine-1-phosphate receptor 2 in the CNS demonstrates sexually dimorphic expression.
Org Biomol Chem
; 13(29): 7928-39, 2015 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26108234