Detalhe da pesquisa
1.
A "Prozone-Like" Effect Influences the Efficacy of the Monoclonal Antibody ABT-700 against the Hepatocyte Growth Factor Receptor.
Pharmacology
; 100(5-6): 229-242, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28743107
2.
Genetic inhibition of the atypical kinase Wee1 selectively drives apoptosis of p53 inactive tumor cells.
BMC Cancer
; 14: 430, 2014 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24927813
3.
Correlation of tumor growth suppression and methionine aminopetidase-2 activity blockade using an orally active inhibitor.
Proc Natl Acad Sci U S A
; 105(6): 1838-43, 2008 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-18252827
4.
Imidazo[2,1-b]thiazoles: multitargeted inhibitors of both the insulin-like growth factor receptor and members of the epidermal growth factor family of receptor tyrosine kinases.
Bioorg Med Chem Lett
; 20(8): 2452-5, 2010 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20346655
5.
Reducing agent-mediated precipitation of high-abundance plasma proteins.
Anal Biochem
; 387(2): 184-93, 2009 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19454248
6.
Development of multitargeted inhibitors of both the insulin-like growth factor receptor (IGF-IR) and members of the epidermal growth factor family of receptor tyrosine kinases.
Bioorg Med Chem Lett
; 19(6): 1718-21, 2009 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19217287
7.
Identification of Ras-related nuclear protein, targeting protein for xenopus kinesin-like protein 2, and stearoyl-CoA desaturase 1 as promising cancer targets from an RNAi-based screen.
Cancer Res
; 67(9): 4390-8, 2007 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17483353
8.
Insulin-like growth factor-1 receptor and ErbB kinase inhibitor combinations block proliferation and induce apoptosis through cyclin D1 reduction and Bax activation.
J Biol Chem
; 283(35): 23721-30, 2008 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-18559346
9.
Discovery, identification, and characterization of candidate pharmacodynamic markers of methionine aminopeptidase-2 inhibition.
J Proteome Res
; 7(11): 4807-20, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18828628