Detalhe da pesquisa
1.
A Phase 1 and 2 study of Filanesib alone and in combination with low-dose dexamethasone in relapsed/refractory multiple myeloma.
Cancer
; 123(23): 4617-4630, 2017 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28817190
2.
The kinesin spindle protein inhibitor filanesib enhances the activity of pomalidomide and dexamethasone in multiple myeloma.
Haematologica
; 102(12): 2113-2124, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28860344
3.
Protein Kinase A Opposes the Phosphorylation-dependent Recruitment of Glycogen Synthase Kinase 3ß to A-kinase Anchoring Protein 220.
J Biol Chem
; 290(32): 19445-57, 2015 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26088133
4.
A phase 1 dose-escalation study of filanesib plus bortezomib and dexamethasone in patients with recurrent/refractory multiple myeloma.
Cancer
; 122(21): 3327-3335, 2016 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27433944
5.
Anchored protein kinase A recruitment of active Rac GTPase.
J Biol Chem
; 286(25): 22113-21, 2011 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21460214
6.
AKAP220 protein organizes signaling elements that impact cell migration.
J Biol Chem
; 286(45): 39269-81, 2011 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21890631
7.
Filanesib plus bortezomib and dexamethasone in relapsed/refractory t(11;14) and 1q21 gain multiple myeloma.
Cancer Med
; 11(2): 358-370, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34921527
8.
Loss of AKAP150 perturbs distinct neuronal processes in mice.
Proc Natl Acad Sci U S A
; 105(34): 12557-62, 2008 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-18711127
9.
Spindle checkpoint proteins Mad1 and Mad2 are required for cytostatic factor-mediated metaphase arrest.
J Cell Biol
; 163(6): 1231-42, 2003 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-14691134
10.
The spindle checkpoint kinase bub1 and cyclin e/cdk2 both contribute to the establishment of meiotic metaphase arrest by cytostatic factor.
Curr Biol
; 12(12): 1027-33, 2002 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-12123578
11.
The mechanism of CSF arrest in vertebrate oocytes.
Mol Cell Endocrinol
; 187(1-2): 173-8, 2002 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-11988325
12.
Pim-1 protein kinase is nuclear in Burkitt's lymphoma: nuclear localization is necessary for its biologic effects.
Anticancer Res
; 23(1A): 167-78, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-12680209
13.
Mcl-1 stability determines mitotic cell fate of human multiple myeloma tumor cells treated with the kinesin spindle protein inhibitor ARRY-520.
Mol Cancer Ther
; 9(7): 2046-56, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20571074
14.
ARRY-520, a novel KSP inhibitor with potent activity in hematological and taxane-resistant tumor models.
Anticancer Res
; 29(11): 4373-80, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20032381
15.
Tales of how great drugs were brought down by a flawed rationale--letter.
Clin Cancer Res
; 19(5): 1302, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23393075
16.
Under arrest: cytostatic factor (CSF)-mediated metaphase arrest in vertebrate eggs.
Genes Dev
; 17(6): 683-710, 2003 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12651887