Detalhe da pesquisa
1.
SARS-CoV-2 ORF3a expression in brain disrupts the autophagy-lysosomal pathway, impairs sphingolipid homeostasis, and drives neuropathogenesis.
FASEB J
; 37(5): e22919, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37071464
2.
Sialidase NEU3 action on GM1 ganglioside is neuroprotective in GM1 gangliosidosis.
J Lipid Res
; 64(12): 100463, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37871851
3.
A genome-wide CRISPR/Cas9 screen reveals that the aryl hydrocarbon receptor stimulates sphingolipid levels.
J Biol Chem
; 295(13): 4341-4349, 2020 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32029474
4.
De Novo Sphingolipid Biosynthesis Is Required for Adipocyte Survival and Metabolic Homeostasis.
J Biol Chem
; 292(9): 3929-3939, 2017 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28100772
5.
Sphingosine-1-phosphate Phosphatase 2 Regulates Pancreatic Islet ß-Cell Endoplasmic Reticulum Stress and Proliferation.
J Biol Chem
; 291(23): 12029-38, 2016 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27059959
6.
Autophagy regulates sphingolipid levels in the liver.
J Lipid Res
; 55(12): 2521-31, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25332431
7.
Sphingosine-1-phosphate phosphatase 1 regulates keratinocyte differentiation and epidermal homeostasis.
J Biol Chem
; 288(25): 18381-91, 2013 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23637227
8.
Sphingosine-1-phosphate lyase deficiency produces a pro-inflammatory response while impairing neutrophil trafficking.
J Biol Chem
; 286(9): 7348-58, 2011 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21173151
9.
The Complement Regulator Susd4 Influences Nervous-System Function and Neuronal Morphology in Mice.
iScience
; 23(3): 100957, 2020 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32179479
10.
S1P1 receptor expression regulates emergence of NKT cells in peripheral tissues.
FASEB J
; 22(1): 307-15, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17785606
11.
The Ormdl genes regulate the sphingolipid synthesis pathway to ensure proper myelination and neurologic function in mice.
Elife
; 82019 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31880535
12.
A plasma membrane pool of phosphatidylinositol 4-phosphate is generated by phosphatidylinositol 4-kinase type-III alpha: studies with the PH domains of the oxysterol binding protein and FAPP1.
Mol Biol Cell
; 16(3): 1282-95, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15635101
13.
S1P1 receptor directs the release of immature B cells from bone marrow into blood.
J Exp Med
; 207(5): 1113-24, 2010 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-20404103
14.
Sphingosine kinase 1 and sphingosine-1-phosphate receptor 2 are vital to recovery from anaphylactic shock in mice.
J Clin Invest
; 120(5): 1429-40, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20407207
15.
Design of drug-resistant alleles of type-III phosphatidylinositol 4-kinases using mutagenesis and molecular modeling.
Biochemistry
; 47(6): 1599-607, 2008 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-18205404
16.
Characterization of type II phosphatidylinositol 4-kinase isoforms reveals association of the enzymes with endosomal vesicular compartments.
J Biol Chem
; 277(22): 20041-50, 2002 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-11923287
17.
Inositol lipid binding and membrane localization of isolated pleckstrin homology (PH) domains. Studies on the PH domains of phospholipase C delta 1 and p130.
J Biol Chem
; 277(30): 27412-22, 2002 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-12019260