Detalhe da pesquisa
1.
Chronic Activation of Liver X Receptor Sensitizes Mice to High Cholesterol Diet-Induced Gut Toxicity.
Mol Pharmacol
; 94(4): 1145-1154, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30045953
2.
Preclinical models of nicotinamide phosphoribosyltransferase inhibitor-mediated hematotoxicity and mitigation by co-treatment with nicotinic acid.
Toxicol Mech Methods
; 25(3): 201-11, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25894564
3.
Activation of liver X receptor increases acetaminophen clearance and prevents its toxicity in mice.
Hepatology
; 54(6): 2208-17, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21898498
4.
Characterization of rat liver proteins adducted by reactive metabolites of menthofuran.
Chem Res Toxicol
; 25(11): 2301-9, 2012 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23106769
5.
Identification of a kinase profile that predicts chromosome damage induced by small molecule kinase inhibitors.
PLoS Comput Biol
; 5(7): e1000446, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19629159
6.
Activation of liver X receptor sensitizes mice to gallbladder cholesterol crystallization.
Hepatology
; 47(4): 1331-42, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18318438
7.
Evaluation of the GreenScreen GADD45alpha-GFP indicator assay with non-proprietary and proprietary compounds.
Mutat Res
; 672(1): 10-6, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18812235
8.
Function of CSF1 and IL34 in Macrophage Homeostasis, Inflammation, and Cancer.
Front Immunol
; 10: 2019, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31552020
9.
Estrogen deprivation and inhibition of breast cancer growth in vivo through activation of the orphan nuclear receptor liver X receptor.
Mol Endocrinol
; 21(8): 1781-90, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17536009
10.
Enzalutamide for the Treatment of Androgen Receptor-Expressing Triple-Negative Breast Cancer.
J Clin Oncol
; 36(9): 884-890, 2018 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29373071
11.
Androgen Receptor Immunohistochemistry as a Companion Diagnostic Approach to Predict Clinical Response to Enzalutamide in Triple-Negative Breast Cancer.
JCO Precis Oncol
; 1: 1-19, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-35172518
12.
Potential mechanisms for thrombocytopenia development with trastuzumab emtansine (T-DM1).
Clin Cancer Res
; 21(1): 123-33, 2015 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25370470
13.
Retinal toxicity, in vivo and in vitro, associated with inhibition of nicotinamide phosphoribosyltransferase.
Toxicol Sci
; 144(1): 163-72, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25505128
14.
Direct reprogramming of human fibroblasts to hepatocyte-like cells by synthetic modified mRNAs.
PLoS One
; 9(6): e100134, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24963715
15.
Improving risk assessment.
Sci Transl Med
; 4(159): 159ps22, 2012 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23136041
16.
Mechanism of subendocardial cell proliferation in the rat and relevance for understanding drug-induced valvular heart disease in humans.
Exp Toxicol Pathol
; 62(6): 607-13, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19781924
17.
Drug discovery perspective of chemical-driven mouse mutagenesis.
Drug Discov Today
; 8(5): 199, 2003 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12634009
18.
Orphan nuclear receptor-mediated xenobiotic regulation in drug metabolism.
Drug Discov Today
; 9(10): 442-9, 2004 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15109949
19.
In vitro to in vivo concordance of a high throughput assay of bone marrow toxicity across a diverse set of drug candidates.
Toxicol Lett
; 188(2): 98-103, 2009 Jul 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-19446241
20.
Activation of LXRs prevents bile acid toxicity and cholestasis in female mice.
Hepatology
; 45(2): 422-32, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17256725