Detalhe da pesquisa
1.
Functional Distinction between Human and Mouse Sodium-Coupled Citrate Transporters and Its Biologic Significance: An Attempt for Structural Basis Using a Homology Modeling Approach.
Chem Rev
; 121(9): 5359-5377, 2021 05 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33040525
2.
Crystal structure of the human sterol transporter ABCG5/ABCG8.
Nature
; 533(7604): 561-4, 2016 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27144356
3.
A home run for human NaCT/SLC13A5/INDY: cryo-EM structure and homology model to predict transport mechanisms, inhibitor interactions and mutational defects.
Biochem J
; 478(11): 2051-2057, 2021 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34101804
4.
Functional analysis of a species-specific inhibitor selective for human Na+-coupled citrate transporter (NaCT/SLC13A5/mINDY).
Biochem J
; 477(21): 4149-4165, 2020 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33079129
5.
Substrate-induced conformational changes in the nucleotide-binding domains of lipid bilayer-associated P-glycoprotein during ATP hydrolysis.
J Biol Chem
; 292(50): 20412-20424, 2017 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29018094
6.
Structural stability of purified human CFTR is systematically improved by mutations in nucleotide binding domain 1.
Biochim Biophys Acta Biomembr
; 1860(5): 1193-1204, 2018 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-29425673
7.
Specific stabilization of CFTR by phosphatidylserine.
Biochim Biophys Acta Biomembr
; 1859(2): 289-293, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27913277
8.
Interactions and cooperativity between P-glycoprotein structural domains determined by thermal unfolding provides insights into its solution structure and function.
Biochim Biophys Acta Biomembr
; 1859(1): 48-60, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27783926
9.
Nucleotide dependence of the dimerization of ATP binding cassette nucleotide binding domains.
Biochem Biophys Res Commun
; 480(2): 268-272, 2016 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27765627
10.
Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.
Proc Natl Acad Sci U S A
; 110(33): 13386-91, 2013 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23901103
11.
A survey of detergents for the purification of stable, active human cystic fibrosis transmembrane conductance regulator (CFTR).
Biochim Biophys Acta
; 1838(11): 2825-37, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25065669
12.
Snapshots of ligand entry, malleable binding and induced helical movement in P-glycoprotein.
Acta Crystallogr D Biol Crystallogr
; 71(Pt 3): 732-41, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25760620
13.
Understanding polyspecificity of multidrug ABC transporters: closing in on the gaps in ABCB1.
Trends Biochem Sci
; 35(1): 36-42, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19819701
14.
P-glycoprotein is fully active after multiple tryptophan substitutions.
Biochim Biophys Acta
; 1828(3): 1159-68, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23261390
15.
Molecular phenotypes segregate missense mutations in SLC13A5 Epilepsy.
bioRxiv
; 2024 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38826402
16.
Lipid environment determines the drug-stimulated ATPase activity of P-glycoprotein.
Front Mol Biosci
; 10: 1141081, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36911528
17.
Specific lipids modulate the transporter associated with antigen processing (TAP).
J Biol Chem
; 286(15): 13346-56, 2011 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21357424
18.
Peptide Tags and Domains for Expression and Detection of Mammalian Membrane Proteins at the Cell Surface.
Methods Mol Biol
; 2507: 337-358, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35773591
19.
Expression of Cloned Genes in Pichia pastoris Using the Methanol-Inducible Promoter AOX1.
Cold Spring Harb Protoc
; 2021(1)2021 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33397779
20.
Preparation of Cell Extracts for Purification of Proteins Expressed in Pichia pastoris.
Cold Spring Harb Protoc
; 2021(1)2021 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33397780