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1.
Mol Genet Genomics ; 295(3): 579-589, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-31932897

RESUMO

We have determined the distribution of Y-chromosomal haplotypes and haplogroups in the Yong population, one of the largest and well-known ethnic groups that began migrating southward from China to Thailand centuries ago. Their unique mass migration pattern provided great opportunities for researchers to study the genetic links of the transboundary migration movements among the peoples of China, Myanmar and Thailand. We analysed relevant male-specific markers, such as Y-STRs and Y-SNPs, and the distribution of 23 Y-STRs of 111 Yong individuals and 116 nearby ethnic groups including the Shan, Northern Thai, Lawa, Lua, Skaw, Pwo and Padong groups. We found that the general haplogroup distribution values were similar among different populations; however, the haplogroups O1b-M268 and O2-M112 constituted the vast majority of these values. In contrast with previous maternal lineage studies, the paternal lineage of the Yong did not relate to the Xishuangbanna Dai people, who represent their historically documented ancestors. However, they did display a close genetic affinity to other prehistoric Tai-Kadai speaking groups in China such as the Zhuang and Bouyei. Low degrees of genetic admixture within the populations who belonged to the Austroasiatic and Sino-Tibetan linguistic families were observed in the gene pool of the Yong populations. Resettlement in northern Thailand in the early part of the nineteenth century AD, by way of mass migration trend, was able to preserve the Yong's ancestral genetic background in terms of the way they had previously lived in China and Myanmar. Our study has revealed similar genetic structures among ethnic populations in northern Thailand and southern China, and has identified and emphasized an ancient Tai-Kadai patrilineal ancestry line in the Yong ethnic group.


Assuntos
Cromossomos Humanos Y/genética , DNA Mitocondrial/genética , Etnicidade/genética , Variação Genética , Genética Populacional , Haplótipos , Herança Paterna , Migração Humana , Humanos , Masculino , Tailândia
2.
Mol Genet Genomics ; 294(4): 919-930, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-30929049

RESUMO

According to genetic studies, the Hungarian Y-chromosomal gene pool significantly differs from other Uralic-speaking populations. Hungarians possess a significant frequency of haplogroup R1a-Z280 and a low frequency of haplogroup N-Tat, which is common among other Uralic-speaking populations. Based on this evidence, we further worked to define the links between the linguistically related Hungarian, Mansi and Bashkirian Mari populations. Samples were collected from 45 Bashkirian Mari and 36 Southern Mansi males in the Ural region. We analyzed male-specific markers including 23 STRs and 36 SNPs, which reflect past and recent paternal genetic history. We found that the haplogroup distribution of the two population samples showed high genetic similarity to each other except for the N-Tat* and R1a-Z93 haplogroups in the Bashkirian Mari males. On the MDS plots constructed from Fst- and Rst-genetic distances, the Bashkirian Mari and Southern Mansi population groups showed close genetic affinities with the Khanty, Northern Mansi, Mari, and Estonian populations. For phylogenetic studies, networks were constructed for the most frequent haplogroups in both populations together with other Eurasian populations. Both populations shared common haplotypes within haplogroups R1a-Z280 or N-L1034 with Hungarian speakers, suggesting a common paternal genetic footprint that arose in prehistoric or historic times. Overall, the Hungarian, Mansi, and Bashkirian Mari populations have a much more complex genetic history than the traditional linguistic model or history would suggest. Further studies are needed to clarify the common genetic profiles may have been acquired directly or indirectly during the more or less known their history.


Assuntos
Cromossomos Humanos Y/genética , Etnicidade/genética , Repetições de Microssatélites , Polimorfismo de Nucleotídeo Único , Pool Gênico , Genética Populacional , Haplótipos , Humanos , Hungria/etnologia , Masculino , Filogenia
3.
Biol Futur ; 71(1-2): 131-136, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-34554521

RESUMO

István Sándor was a monk and deeply impressed by the spirituality of the Salesian Society. On 24 July 1946 he made his perpetual votes as a Salesian brother. In 1950 the Communist Party banned the operation of religious orders including the Salesian Order. In 1951 the Internal Security Corps was informed about "illegal" activity of István Sándor. He was arrested on 28 July 1952 and sentenced to death by hanging. He was beatified by Pope Francis in 2013. On 12 November 2018 the grave was opened and bones extracted belonging to six individuals. First, forensic anthropological studies were done. For DNA analysis, teeth and right femurs were selected. DNA extraction method was developed by us. Y-chromosomal and autosomal STR profiles were determined from teeth and bones and reference samples. Based on age and height estimates, the bones that could not belong to István Sándor were excluded. The Blessed István Sándor does not have any living relatives. Envelopes and postage stamps were chosen as reference samples from the years 1942 and 1950. We have received full DNA profiles from teeth, but partial profiles from the envelope and the stamp. Genetic investigations performed support the hypothesis that the bone remains, which were exhumed from the mass grave including relics of putative István Sándor, really belong to the Blessed István Sándor who was executed on 08 June 1953 by the Communist Regime.


Assuntos
Osso e Ossos/química , Catolicismo , DNA/química , DNA/genética , Cromossomos Humanos Y , Impressões Digitais de DNA/métodos , Exumação , Antropologia Forense , Humanos , Masculino , Dente
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