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1.
Sensors (Basel) ; 23(15)2023 Aug 04.
Artigo em Inglês | MEDLINE | ID: mdl-37571727

RESUMO

Three-dimensional (3D) cameras used for gait assessment obviate the need for bodily markers or sensors, making them particularly interesting for clinical applications. Due to their limited field of view, their application has predominantly focused on evaluating gait patterns within short walking distances. However, assessment of gait consistency requires testing over a longer walking distance. The aim of this study is to validate the accuracy for gait assessment of a previously developed method that determines walking spatiotemporal parameters and kinematics measured with a 3D camera mounted on a mobile robot base (ROBOGait). Walking parameters measured with this system were compared with measurements with Xsens IMUs. The experiments were performed on a non-linear corridor of approximately 50 m, resembling the environment of a conventional rehabilitation facility. Eleven individuals exhibiting normal motor function were recruited to walk and to simulate gait patterns representative of common neurological conditions: Cerebral Palsy, Multiple Sclerosis, and Cerebellar Ataxia. Generalized estimating equations were used to determine statistical differences between the measurement systems and between walking conditions. When comparing walking parameters between paired measures of the systems, significant differences were found for eight out of 18 descriptors: range of motion (ROM) of trunk and pelvis tilt, maximum knee flexion in loading response, knee position at toe-off, stride length, step time, cadence; and stance duration. When analyzing how ROBOGait can distinguish simulated pathological gait from physiological gait, a mean accuracy of 70.4%, a sensitivity of 49.3%, and a specificity of 74.4% were found when compared with the Xsens system. The most important gait abnormalities related to the clinical conditions were successfully detected by ROBOGait. The descriptors that best distinguished simulated pathological walking from normal walking in both systems were step width and stride length. This study underscores the promising potential of 3D cameras and encourages exploring their use in clinical gait analysis.


Assuntos
Marcha , Caminhada , Humanos , Marcha/fisiologia , Caminhada/fisiologia , Extremidade Inferior , Joelho , Articulação do Joelho , Fenômenos Biomecânicos
2.
Sensors (Basel) ; 21(8)2021 Apr 13.
Artigo em Inglês | MEDLINE | ID: mdl-33924403

RESUMO

Gait analysis has traditionally been carried out in a laboratory environment using expensive equipment, but, recently, reliable, affordable, and wearable sensors have enabled integration into clinical applications as well as use during activities of daily living. Real-time gait analysis is key to the development of gait rehabilitation techniques and assistive devices such as neuroprostheses. This article presents a systematic review of wearable sensors and techniques used in real-time gait analysis, and their application to pathological gait. From four major scientific databases, we identified 1262 articles of which 113 were analyzed in full-text. We found that heel strike and toe off are the most sought-after gait events. Inertial measurement units (IMU) are the most widely used wearable sensors and the shank and foot are the preferred placements. Insole pressure sensors are the most common sensors for ground-truth validation for IMU-based gait detection. Rule-based techniques relying on threshold or peak detection are the most widely used gait detection method. The heterogeneity of evaluation criteria prevented quantitative performance comparison of all methods. Although most studies predicted that the proposed methods would work on pathological gait, less than one third were validated on such data. Clinical applications of gait detection algorithms were considered, and we recommend a combination of IMU and rule-based methods as an optimal solution.


Assuntos
Atividades Cotidianas , Dispositivos Eletrônicos Vestíveis , Fenômenos Biomecânicos , Marcha , Análise da Marcha , Humanos
3.
J Neuroeng Rehabil ; 17(1): 81, 2020 06 25.
Artigo em Inglês | MEDLINE | ID: mdl-32586398

RESUMO

BACKGROUND: Gait training with partial body weight support (BWS) has become an established rehabilitation technique. Besides passive unloading mechanisms such as springs or counterweights, also active systems that allow rendering constant or modulated vertical forces have been proposed. However, only pilot studies have been conducted to compare different unloading or modulation strategies, and conducting experimental studies is costly and time-consuming. Simulation models that predict the influence of unloading force on human walking may help select the most promising candidates for further evaluation. However, the reliability of simulation results depends on the chosen gait model. The purpose of this paper is two-fold: First, using human experimental data, we evaluate the accuracy of some of the most prevalent walking models in replicating human walking under the influence of Constant-Force BWS: The Simplest Walking model (SW), the Spring-Loaded Inverted Pendulum model (SLIP) and the Muscle-Reflex (MR) gait model. Second, three realizations of BWS, based on Constant-Force (CF), Counterweight (CW) and Tuned-Spring (TS) approaches, are compared to each other in terms of their influence on gait parameters. METHODS: We conducted simulations in Matlab/Simulink to model the behaviour of each gait model under all three BWS conditions. Nine simulations were undertaken in total and gait parameter response was analysed in each case. Root mean square error (mrmse) w.r.t human data was used to compare the accuracy of gait models. The metrics of interest were spatiotemporal parameters and the vertical ground reaction forces. To scrutinize the BWS strategies, loss of dynamic similarity was calculated in terms of root mean square difference in gait dynamics (Δgd) with respect to the reference gait under zero unloading. The gait dynamics were characterized by a dimensionless number Modela-w. RESULTS: SLIP model showed the lowest mrmse for 6 out of 8 gait parameters and for 1 other, the mrmse value were comparable to the MR model; SW model had the highest mrmse. Out of three BWS strategies, Tuned-Spring strategies led to the lowest Δgd values. CONCLUSIONS: The results of this work demonstrate the usefulness of gait models for BWS simulation and suggest the SLIP model to be more suitable for BWS simulations than the Simplest Walker and the Muscle-reflex models. Further, the Tuned-Spring approach appears to cause less distortions to the gait pattern than the more established Counterweight and Constant-Force approaches and merits experimental verification.


Assuntos
Simulação por Computador , Transtornos Neurológicos da Marcha/reabilitação , Marcha/fisiologia , Simulação de Ausência de Peso/métodos , Benchmarking , Fenômenos Biomecânicos , Peso Corporal/fisiologia , Terapia por Exercício/métodos , Humanos , Reprodutibilidade dos Testes , Caminhada/fisiologia , Simulação de Ausência de Peso/normas
4.
Sensors (Basel) ; 19(20)2019 Oct 18.
Artigo em Inglês | MEDLINE | ID: mdl-31635375

RESUMO

Gait and balance impairments are linked with reduced mobility and increased risk of falling. Wearable sensing technologies, such as inertial measurement units (IMUs), may augment clinical assessments by providing continuous, high-resolution data. This study tested and validated the utility of a single IMU to quantify gait and balance features during routine clinical outcome tests, and evaluated changes in sensor-derived measurements with age, sex, height, and weight. Age-ranged, healthy individuals (N = 49, 20-70 years) wore a lower back IMU during the 10 m walk test (10MWT), Timed Up and Go (TUG), and Berg Balance Scale (BBS). Spatiotemporal gait parameters computed from the sensor data were validated against gold standard measures, demonstrating excellent agreement for stance time, step time, gait velocity, and step count (intraclass correlation (ICC) > 0.90). There was good agreement for swing time (ICC = 0.78) and moderate agreement for step length (ICC = 0.68). A total of 184 features were calculated from the acceleration and angular velocity signals across these tests, 36 of which had significant correlations with age. This approach was also demonstrated for an individual with stroke, providing higher resolution information about balance, gait, and mobility than the clinical test scores alone. Leveraging mobility data from wireless, wearable sensors can help clinicians and patients more objectively pinpoint impairments, track progression, and set personalized goals during and after rehabilitation.


Assuntos
Marcha , Equilíbrio Postural , Adulto , Idoso , Algoritmos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Avaliação de Resultados em Cuidados de Saúde , Acidente Vascular Cerebral/fisiopatologia , Reabilitação do Acidente Vascular Cerebral , Dispositivos Eletrônicos Vestíveis , Adulto Jovem
5.
J Neuroeng Rehabil ; 15(1): 53, 2018 06 20.
Artigo em Inglês | MEDLINE | ID: mdl-29925400

RESUMO

BACKGROUND: Body weight support (BWS) systems have shown promise as rehabilitation tools for neurologically impaired individuals. This paper reviews the experiment-based research on BWS systems with the aim: (1) To investigate the influence of body weight unloading (BWU) on gait characteristics; (2) To study whether the effects of BWS differ between treadmill and overground walking and (3) To investigate if modulated BWU influences gait characteristics less than unmodulated BWU. METHOD: A systematic literature search was conducted in the following search engines: Pubmed, Scopus, Web of Science and Google Scholar. Statistical analysis was used to quantify the effects of BWU on gait parameters. RESULTS: 54 studies of experiments with healthy and neurologically impaired individuals walking in a BWS system were included and 32 of these were used for the statistical analysis. Literature was classified using three distinctions: (1) treadmill or overground walking; (2) the type of subjects and (3) the nature of unloading force. Only 27% studies were based on neurologically impaired subjects; a low number considering that they are the primary user group for BWS systems. The studies included BWU from 5% to 100% and the 30% and 50% BWU conditions were the most widely studied. The number of participants varied from 1 to 28, with an average of 12. It was seen that due to the increase in BWU level, joint moments, muscle activity, energy cost of walking and ground reaction forces (GRF) showed higher reduction compared to gait spatio-temporal and joint kinematic parameters. The influence of BWU on kinematic and spatio-temporal gait parameters appeared to be limited up to 30% unloading. 5 gait characteristics presented different behavior in response to BWU for overground and treadmill walking. Remaining 21 gait characteristics showed similar behavior but different magnitude of change for overground and treadmill walking. Modulated unloading force generally led to less difference from the 0% condition than unmodulated unloading. CONCLUSION: This review has shown that BWU influences all gait characteristics, albeit with important differences between the kinematic, spatio-temporal and kinetic characteristics. BWU showed stronger influence on the kinetic characteristics of gait than on the spatio-temporal parameters and the kinematic characteristics. It was ascertained that treadmill and overground walking can alter the effects of BWU in a different manner. Our results indicate that task-specific gait training is likely to be achievable at a BWU level of 30% and below.


Assuntos
Fenômenos Biomecânicos/fisiologia , Peso Corporal/fisiologia , Marcha/fisiologia , Feminino , Humanos , Masculino , Reabilitação Neurológica
6.
J Neuroeng Rehabil ; 15(1): 73, 2018 08 08.
Artigo em Inglês | MEDLINE | ID: mdl-30089522

RESUMO

The original article [1] contained a major error whereby Figure 1 mistakenly displayed a duplicate of Figure 5.

7.
J Neuroeng Rehabil ; 14(1): 80, 2017 08 14.
Artigo em Inglês | MEDLINE | ID: mdl-28806995

RESUMO

Clinically useful and efficient assessment of balance during standing and walking is especially challenging in patients with neurological disorders. However, rehabilitation robots could facilitate assessment procedures and improve their clinical value. We present a short overview of balance assessment in clinical practice and in posturography. Based on this overview, we evaluate the potential use of robotic tools for such assessment. The novelty and assumed main benefits of using robots for assessment are their ability to assess 'severely affected' patients by providing assistance-as-needed, as well as to provide consistent perturbations during standing and walking while measuring the patient's reactions. We provide a classification of robotic devices on three aspects relevant to their potential application for balance assessment: 1) how the device interacts with the body, 2) in what sense the device is mobile, and 3) on what surface the person stands or walks when using the device. As examples, nine types of robotic devices are described, classified and evaluated for their suitability for balance assessment. Two example cases of robotic assessments based on perturbations during walking are presented. We conclude that robotic devices are promising and can become useful and relevant tools for assessment of balance in patients with neurological disorders, both in research and in clinical use. Robotic assessment holds the promise to provide increasingly detailed assessment that allows to individually tailor rehabilitation training, which may eventually improve training effectiveness.


Assuntos
Doenças do Sistema Nervoso/diagnóstico , Modalidades de Fisioterapia/instrumentação , Equilíbrio Postural , Robótica/métodos , Caminhada , Humanos , Masculino
8.
J Neuroeng Rehabil ; 12: 1, 2015 Jan 05.
Artigo em Inglês | MEDLINE | ID: mdl-25557982

RESUMO

: Technological advancements have led to the development of numerous wearable robotic devices for the physical assistance and restoration of human locomotion. While many challenges remain with respect to the mechanical design of such devices, it is at least equally challenging and important to develop strategies to control them in concert with the intentions of the user.This work reviews the state-of-the-art techniques for controlling portable active lower limb prosthetic and orthotic (P/O) devices in the context of locomotive activities of daily living (ADL), and considers how these can be interfaced with the user's sensory-motor control system. This review underscores the practical challenges and opportunities associated with P/O control, which can be used to accelerate future developments in this field. Furthermore, this work provides a classification scheme for the comparison of the various control strategies.As a novel contribution, a general framework for the control of portable gait-assistance devices is proposed. This framework accounts for the physical and informatic interactions between the controller, the user, the environment, and the mechanical device itself. Such a treatment of P/Os--not as independent devices, but as actors within an ecosystem--is suggested to be necessary to structure the next generation of intelligent and multifunctional controllers.Each element of the proposed framework is discussed with respect to the role that it plays in the assistance of locomotion, along with how its states can be sensed as inputs to the controller. The reviewed controllers are shown to fit within different levels of a hierarchical scheme, which loosely resembles the structure and functionality of the nominal human central nervous system (CNS). Active and passive safety mechanisms are considered to be central aspects underlying all of P/O design and control, and are shown to be critical for regulatory approval of such devices for real-world use.The works discussed herein provide evidence that, while we are getting ever closer, significant challenges still exist for the development of controllers for portable powered P/O devices that can seamlessly integrate with the user's neuromusculoskeletal system and are practical for use in locomotive ADL.


Assuntos
Extremidade Inferior , Aparelhos Ortopédicos , Próteses e Implantes , Desenho de Prótese/métodos , Atividades Cotidianas , Eletromiografia , Marcha , Humanos , Locomoção
9.
Heliyon ; 10(5): e26497, 2024 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-38434412

RESUMO

Background: Pneumatic actuators are widely used in applications like (medical) robots, or prostheses. Pneumatic actuators require a complex manufacturing process and are produced in standardized dimensions to reduce costs. Over the last decade 3D-printing has emerged as a cost-effective and efficient production method in medical applications. 3D-printing can also function as a cost-efficient alternative production method for pneumatic actuators. Objective: The goal of this research is to study the possibility of creating a pneumatic linear actuator with 3D-printing. Furthermore, the aim is to use the advantage of 3D-printing to create pneumatic actuators with non-circular cross-sections. Methodology: To evaluate the performance of a 3D-printed pneumatic actuator, a test setup was designed and built to measure the leakage and sliding friction force. Furthermore, two pneumatic actuators with a non-conventional cross-sectional shape were designed and their performance was tested and compared with a 3D-printed cylindrical pneumatic actuator, since these tests only ran once, the results are more a guideline. During the manufacturing of the cylinders, no post-processing techniques were used. Results: The functioning of a 3D-printed circular pneumatic actuator was proven with low static leakage rates of 2.5%, low dynamic leakage rates of approximately 1%, and a maximum friction force of Image 1. Furthermore, the results show that it is possible to print functioning pneumatic cylinders with a non-cylindrical concave cross-section. The non-conventional cylinders were tested up to Image 2 with maximum dynamic leakage of Image 3. Conclusion: This study demonstrates a method to create functional pneumatic linear actuators with 3D-printing. It was possible to create 3D-printed actuators with a conventional shape, e.g. circular and unconventional shapes e.g. stadium/oval shape and a kidney shape. The leak rates for conventional and unconventional shapes were in the same range. This opens up the world for more design freedom in pneumatic actuators.

10.
PLoS One ; 19(7): e0305564, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38990959

RESUMO

People fall more often when their gait stability is reduced. Gait stability can be directly manipulated by exerting forces or moments onto a person, ranging from simple walking sticks to complex wearable robotics. A systematic review of the literature was performed to determine: What is the level of evidence for different types of mechanical manipulations on improving gait stability? The study was registered at PROSPERO (CRD42020180631). Databases Embase, Medline All, Web of Science Core Collection, Cochrane Central Register of Controlled Trials, and Google Scholar were searched. The final search was conducted on the 1st of December, 2022. The included studies contained mechanical devices that influence gait stability for both impaired and non-impaired subjects. Studies performed with prosthetic devices, passive orthoses, and analysing post-training effects were excluded. An adapted NIH quality assessment tool was used to assess the study quality and risk of bias. Studies were grouped based on the type of device, point of application, and direction of forces and moments. For each device type, a best-evidence synthesis was performed to quantify the level of evidence based on the type of validity of the reported outcome measures and the study quality assessment score. Impaired and non-impaired study participants were considered separately. From a total of 4701 papers, 53 were included in our analysis. For impaired subjects, indicative evidence was found for medio-lateral pelvis stabilisation for improving gait stability, while limited evidence was found for hip joint assistance and canes. For non-impaired subjects, moderate evidence was found for medio-lateral pelvis stabilisation and limited evidence for body weight support. For all other device types, either indicative or insufficient evidence was found for improving gait stability. Our findings also highlight the lack of consensus on outcome measures amongst studies of devices focused on manipulating gait.


Assuntos
Marcha , Humanos , Marcha/fisiologia , Fenômenos Biomecânicos , Acidentes por Quedas/prevenção & controle , Equilíbrio Postural/fisiologia , Robótica/métodos , Caminhada/fisiologia
11.
PLoS One ; 18(2): e0280158, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36809378

RESUMO

Balance recovery after tripping often requires an active adaptation of foot placement. Thus far, few attempts have been made to actively assist forward foot placement for balance recovery employing wearable devices. This study aims to explore the possibilities of active forward foot placement through two paradigms of actuation: assistive moments exerted with the reaction moments either internal or external to the human body, namely 'joint' moments and 'free' moments, respectively. Both paradigms can be applied to manipulate the motion of segments of the body (e.g., the shank or thigh), but joint actuators also exert opposing reaction moments on neighbouring body segments, altering posture and potentially inhibiting tripping recovery. We therefore hypothesised that a free moment paradigm is more effective in assisting balance recovery following tripping. The simulation software SCONE was used to simulate gait and tripping over various ground-fixed obstacles during the early swing phase. To aid forward foot placement, joint moments and free moments were applied either on the thigh to augment hip flexion or on the shank to augment knee extension. Two realizations of joint moments on the hip were simulated, with the reaction moment applied to either the pelvis or the contralateral thigh. The simulation results show that assisting hip flexion with either actuation paradigm on the thigh can result in full recovery of gait with a margin of stability and leg kinematics closely matching the unperturbed case. However, when assisting knee extension with moments on the shank, free moment effectively assist balance but joint moments with the reaction moment on the thigh do not. For joint moments assisting hip flexion, placement of the reaction moment on the contralateral thigh was more effective in achieving the desired limb dynamics than placing the reaction on the pelvis. Poor choice of placement of reaction moments may therefore have detrimental consequences for balance recovery, and removing them entirely (i.e., free moment) could be a more effective and reliable alternative. These results challenge conventional assumptions and may inform the design and development of a new generation of minimalistic wearable devices to promote balance during gait.


Assuntos
Robótica , Humanos , Extremidade Inferior , Perna (Membro) , Articulação do Joelho , Marcha , Fenômenos Biomecânicos
12.
Wearable Technol ; 4: e16, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-38487767

RESUMO

Standing up using one leg is a challenging task for those with a transfemoral amputation, particularly for elderly users with a low activity level. Active prostheses are generally not accessible to this group and available passive prostheses do not support standing up. This article presents the design and evaluation of the "Energy Restoring Intelligent Knee" (ERiK), which stores energy during sit-down in a pneumatic cylinder and returns it during stand-up. We hypothesized that the system would reduce the time needed to perform transitions and also enable higher load sharing by the prosthetic leg. However, the results of an experimental study with seven participants with transfemoral amputation contradict these hypotheses: the participants could neither move faster nor make more use of the prosthetic leg to share their body weight during transitions. We observed that a major obstacle to the useful functionality of the leg was the absence of ankle dorsiflexion - the foot tended to slip during stand-up initiation, such that only low pre-pressures and therefore support levels could be set. The rather binary action of the pneumatics also complicated movement initiation. The lessons learned from this study may be helpful to those seeking to create better designs in the future.

13.
Healthcare (Basel) ; 11(21)2023 Oct 27.
Artigo em Inglês | MEDLINE | ID: mdl-37957986

RESUMO

Falling is a major cause of morbidity, and is often caused by a decrease in postural stability. A key component of postural stability is whole-body centroidal angular momentum, which can be influenced by control moment gyroscopes. In this proof-of-concept study, we explore the influence of our wearable robotic gyroscopic actuator "GyroPack" on the balance performance and gait characteristics of non-impaired individuals (seven female/eight male, 30 ± 7 years, 68.8 ± 8.4 kg). Participants performed a series of balance and walking tasks with and without wearing the GyroPack. The device displayed various control modes, which were hypothesised to positively, negatively, or neutrally impact postural control. When configured as a damper, the GyroPack increased mediolateral standing time and walking distance, on a balance beam, and decreased trunk angular velocity variability, while walking on a treadmill. When configured as a negative damper, both peak trunk angular rate and trunk angular velocity variability increased during treadmill walking. This exploratory study shows that gyroscopic actuators can influence balance and gait kinematics. Our results mirror the findings of our earlier studies; though, with more than 50% mass reduction of the device, practical and clinical applicability now appears within reach.

14.
J Neuroeng Rehabil ; 9: 65, 2012 Sep 07.
Artigo em Inglês | MEDLINE | ID: mdl-22953989

RESUMO

BACKGROUND: Stroke is the most common cause of disability in the developed world and can severely degrade walking function. Robot-driven gait therapy can provide assistance to patients during training and offers a number of advantages over other forms of therapy. These potential benefits do not, however, seem to have been fully realised as of yet in clinical practice. OBJECTIVES: This review determines ways in which robot-driven gait technology could be improved in order to achieve better outcomes in gait rehabilitation. METHODS: The literature on gait impairments caused by stroke is reviewed, followed by research detailing the different pathways to recovery. The outcomes of clinical trials investigating robot-driven gait therapy are then examined. Finally, an analysis of the literature focused on the technical features of the robot-based devices is presented. This review thus combines both clinical and technical aspects in order to determine the routes by which robot-driven gait therapy could be further developed. CONCLUSIONS: Active subject participation in robot-driven gait therapy is vital to many of the potential recovery pathways and is therefore an important feature of gait training. Higher levels of subject participation and challenge could be promoted through designs with a high emphasis on robotic transparency and sufficient degrees of freedom to allow other aspects of gait such as balance to be incorporated.


Assuntos
Marcha/fisiologia , Robótica , Reabilitação do Acidente Vascular Cerebral , Terapia por Exercício , Transtornos Neurológicos da Marcha/etiologia , Transtornos Neurológicos da Marcha/reabilitação , Humanos , Educação Física e Treinamento , Melhoria de Qualidade , Acidente Vascular Cerebral/fisiopatologia , Resultado do Tratamento
15.
J Neuroeng Rehabil ; 9: 31, 2012 May 31.
Artigo em Inglês | MEDLINE | ID: mdl-22650320

RESUMO

BACKGROUND: Functional training is becoming the state-of-the-art therapy approach for rehabilitation of individuals after stroke and spinal cord injury. Robot-aided treadmill training reduces personnel effort, especially when treating severely affected patients. Improving rehabilitation robots towards more patient-cooperative behavior may further increase the effects of robot-aided training. This pilot study aims at investigating the feasibility of applying patient-cooperative robot-aided gait rehabilitation to stroke and incomplete spinal cord injury during a therapy period of four weeks. Short-term effects within one training session as well as the effects of the training on walking function are evaluated. METHODS: Two individuals with chronic incomplete spinal cord injury and two with chronic stroke trained with the Lokomat gait rehabilitation robot which was operated in a new, patient-cooperative mode for a period of four weeks with four training sessions of 45 min per week. At baseline, after two and after four weeks, walking function was assessed with the ten meter walking test. Additionally, muscle activity of the major leg muscles, heart rate and the Borg scale were measured under different walking conditions including a non-cooperative position control mode to investigate the short-term effects of patient-cooperative versus non-cooperative robot-aided gait training. RESULTS: Patient-cooperative robot-aided gait training was tolerated well by all subjects and performed without difficulties. The subjects trained more actively and with more physiological muscle activity than in a non-cooperative position-control mode. One subject showed a significant and relevant increase of gait speed after the therapy, the three remaining subjects did not show significant changes. CONCLUSIONS: Patient-cooperative robot-aided gait training is feasible in clinical practice and overcomes the main points of criticism against robot-aided gait training: It enables patients to train in an active, variable and more natural way. The limited number of subjects in this pilot trial does not permit valid conclusions on the effect of patient-cooperative robot-aided gait training on walking function. A large, possibly multi-center randomized controlled clinical trial is required to shed more light on this question.


Assuntos
Transtornos Neurológicos da Marcha/reabilitação , Marcha/fisiologia , Robótica , Adolescente , Adulto , Idoso , Peso Corporal/fisiologia , Estudos de Viabilidade , Retroalimentação Psicológica , Feminino , Humanos , Modelos Lineares , Masculino , Pessoa de Meia-Idade , Paresia/etiologia , Paresia/reabilitação , Cooperação do Paciente , Educação Física e Treinamento , Esforço Físico , Projetos Piloto , Traumatismos da Medula Espinal/reabilitação , Reabilitação do Acidente Vascular Cerebral , Resultado do Tratamento , Interface Usuário-Computador , Caminhada , Adulto Jovem
16.
J Neuroeng Rehabil ; 9: 30, 2012 May 30.
Artigo em Inglês | MEDLINE | ID: mdl-22647145

RESUMO

Clinical scores represent the gold standard in characterizing the clinical condition of patients in vegetative or minimally conscious state. However, they suffer from problems of sensitivity, specificity, subjectivity and inter-rater reliability.In this feasibility study, objective measures including physiological and neurophysiological signals are used to quantify the clinical state of 13 low-responsive patients. A linear regression method was applied in nine patients to obtain fixed regression coefficients for the description of the clinical state. The statistical model was extended and evaluated with four patients of another hospital. A linear mixed models approach was introduced to handle the challenges of data sets obtained from different locations.Using linear backward regression 12 variables were sufficient to explain 74.4% of the variability in the change of the clinical scores. Variables based on event-related potentials and electrocardiogram account for most of the variability.These preliminary results are promising considering that this is the first attempt to describe the clinical state of low-responsive patients in such a global and quantitative way. This new model could complement the clinical scores based on objective measurements in order to increase diagnostic reliability. Nevertheless, more patients are necessary to prove the conclusions of a statistical model with 12 variables.


Assuntos
Testes Neuropsicológicos , Estado Vegetativo Persistente/diagnóstico , Estado Vegetativo Persistente/fisiopatologia , Adulto , Estudos de Viabilidade , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem
17.
IEEE Int Conf Rehabil Robot ; 2022: 1-6, 2022 07.
Artigo em Inglês | MEDLINE | ID: mdl-36176139

RESUMO

Trunk motor control is essential for the proper functioning of the upper extremities and is an important predictor of gait capacity in children with delayed development. Early diagnosis and intervention could increase the trunk motor capabilities in later life, but current tools used to assess the level of trunk motor control are largely subjective and many lack the sensitivity to accurately monitor development and the effects of therapy. Inertial measurement units could yield an objective quantitative assessment that is inexpensive and easy-to-implement. We hypothesized that root mean square of jerk, a proxy for movement smoothness, could be used to distinguish age and thereby presumed motor development. We attached a sensor to the trunks of six young children with no known developmental deficits. Root mean square of jerk decreases with age, up to 24 months, and is correlated to a more established method, i.e., center-of-pressure velocity, as well as other standard inertial measurement unit outputs. This metric therefore shows potential as a method to differentiate trunk motor control levels.


Assuntos
Marcha , Movimento , Criança , Pré-Escolar , Humanos , Lactente , Monitorização Fisiológica , Extremidade Superior
18.
Sci Rep ; 10(1): 10412, 2020 06 26.
Artigo em Inglês | MEDLINE | ID: mdl-32591577

RESUMO

Gyroscopic actuators are appealing for wearable applications due to their ability to provide overground balance support without obstructing the legs. Multiple wearable robots using this actuation principle have been proposed, but none has yet been evaluated with humans. Here we use the GyBAR, a backpack-like prototype portable robot, to investigate the hypothesis that the balance of both healthy and chronic stroke subjects can be augmented through moments applied to the upper body. We quantified balance performance in terms of each participant's ability to walk or remain standing on a narrow support surface oriented to challenge stability in either the frontal or the sagittal plane. By comparing candidate balance controllers, it was found that effective assistance did not require regulation to a reference posture. A rotational viscous field increased the distance healthy participants could walk along a 30mm-wide beam by a factor of 2.0, compared to when the GyBAR was worn but inactive. The same controller enabled individuals with chronic stroke to remain standing for a factor of 2.5 longer on a narrow block. Due to its wearability and versatility of control, the GyBAR could enable new therapy interventions for training and rehabilitation.


Assuntos
Equilíbrio Postural/fisiologia , Robótica , Reabilitação do Acidente Vascular Cerebral/métodos , Caminhada/fisiologia , Dispositivos Eletrônicos Vestíveis , Adulto , Fenômenos Biomecânicos/fisiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Postura/fisiologia
19.
IEEE Int Conf Rehabil Robot ; 2019: 1079-1084, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31374773

RESUMO

Wearable actuators in lower-extremity active orthoses or prostheses have the potential to address a variety of gait disorders. However, whenever conventional joint actuators exert moments on specific limbs, they must simultaneously impose opposing reaction moments on other limbs, which may reduce the desired effects and perturb posture. Momentum exchange actuators exert free moments on individual limbs, potentially overcoming or mitigating these issues.We simulate unperturbed gait to compare conventional joint actuators placed on the knee or hip of the swing leg, and equivalent angular momentum exchange actuators placed on the shank or thigh. Our results indicate that, while conventional joint actuators excel at increasing toe clearance when assisting knee flexion, free moments can yield greater increases in stride length when assisting knee extension or hip flexion.


Assuntos
Marcha/fisiologia , Articulação do Joelho/fisiologia , Membros Artificiais , Articulação do Quadril/fisiologia , Humanos
20.
Soft Robot ; 6(5): 621-630, 2019 10.
Artigo em Inglês | MEDLINE | ID: mdl-31145024

RESUMO

The twisted and coiled polymer muscle (TCPM) has two major benefits: low weight and low cost. Therefore, this new type of actuator is increasingly used in robotic applications where these benefits are relevant. Closed-loop control of these muscles, however, requires additional sensors that add weight and cost, negating the muscles' intrinsic benefits. Self-sensing enables feedback without added sensors. In this article, we investigate the feasibility of using self-sensing in closed-loop control of a Joule-heated muscle. We use a hardware module that is capable of driving the muscle, and simultaneously providing sensor measurements based on inductance. A mathematical model relates the measurements to the deflection. In combination with a simple force model, we can estimate both deflection and force, and control either of them. For a muscle that operates within deflections of [10, 30] mm and forces of [0.32, 0.51] N, our self-sensing method exhibited a 95% confidence interval of 2.14 mm around a mean estimation error of -0.27 mm and 29.0 mN around a mean estimation error of 7.5 mN, for the estimation of, respectively, deflection and force. We conclude that self-sensing in closed-loop control of Joule-heated TCPMs is feasible and may facilitate further deployment of such actuators in applications where low cost and weight are critical.

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