Negative gallium-67 citrate and positive positron emission tomography/computed tomography spleen scans, in Hodgkin's stage IV lymphoma.

An 18-year-old male patient with Hodgkin's lymphoma stage IVB (HL-IVB), is presented. On a follow-up examination a splenic ultrasound scan showed the presence of multiple intense nodules. The gallium-67 citrate, single photon emission tomography scan was negative, while positron emission tomography/computerized tomography (PET/CT) scan with fluoro-18-fluordeoxyglucose was strongly positive. Massive infiltration of the spleen by HL-IVB tissue was confirmed by pathology after splenectomy. Two successive PET/CT studies for follow-up purposes three and twelve months after completion of chemotherapy, were normal.