Detalhe da pesquisa
1.
Preclinical mouse cancer models: a maze of opportunities and challenges.
Cell
; 163(1): 39-53, 2015 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26406370
2.
Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy.
Cell
; 159(1): 80-93, 2014 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-25259922
3.
It takes a (dysfunctional) village to raise a tumor.
Cell
; 135(3): 408-10, 2008 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-18984150
4.
Inactivation of TRP53, PTEN, RB1, and/or CDH1 in the ovarian surface epithelium induces ovarian cancer transformation and metastasis.
Biol Reprod
; 102(5): 1055-1064, 2020 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31930396
5.
Evolutionary etiology of high-grade astrocytomas.
Proc Natl Acad Sci U S A
; 110(44): 17933-8, 2013 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-24114272
6.
Akt-dependent activation of mTORC1 complex involves phosphorylation of mTOR (mammalian target of rapamycin) by IκB kinase α (IKKα).
J Biol Chem
; 289(36): 25227-40, 2014 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24990947
7.
Conditional Aurora A deficiency differentially affects early mouse embryo patterning.
Dev Biol
; 371(1): 77-85, 2012 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22939930
8.
Characterization of an Mtbp Hypomorphic Allele in a Diethylnitrosamine-Induced Liver Carcinogenesis Model.
Cancers (Basel)
; 15(18)2023 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37760565
9.
Astrocyte inactivation of the pRb pathway predisposes mice to malignant astrocytoma development that is accelerated by PTEN mutation.
Cancer Cell
; 1(2): 157-68, 2002 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-12086874
10.
Abrogation of Rb Tumor Suppression Initiates GBM in Differentiated Astrocytes by Driving a Progenitor Cell Program.
Front Oncol
; 12: 904479, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35814428
11.
Distinct Biomarker Profiles and TCR Sequence Diversity Characterize the Response to PD-L1 Blockade in a Mouse Melanoma Model.
Mol Cancer Res
; 19(8): 1422-1436, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33888600
12.
VHL and PTEN loss coordinate to promote mouse liver vascular lesions.
Angiogenesis
; 13(1): 59-69, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20221685
13.
Differential Apaf-1 levels allow cytochrome c to induce apoptosis in brain tumors but not in normal neural tissues.
Proc Natl Acad Sci U S A
; 104(52): 20820-5, 2007 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-18093951
14.
Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy.
Nat Med
; 26(5): 781-791, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32284588
15.
Inactivation of SNF5 cooperates with p53 loss to accelerate tumor formation in Snf5(+/-);p53(+/-) mice.
Mol Carcinog
; 48(12): 1139-48, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19676100
16.
Optimization of self-complementary AAV vectors for liver-directed expression results in sustained correction of hemophilia B at low vector dose.
Mol Ther
; 16(2): 280-9, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18059373
17.
Engineering and selection of shuffled AAV genomes: a new strategy for producing targeted biological nanoparticles.
Mol Ther
; 16(7): 1252-60, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18500254
18.
Engineering and Selection of Shuffled AAV Genomes: A New Strategy for Producing Targeted Biological Nanoparticles.
Mol Ther
; 16(7): 1252-1260, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28178482
19.
Tumor-specific cooperation of retinoblastoma protein family and Snf5 inactivation.
Cancer Res
; 67(7): 3002-9, 2007 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17409406
20.
A dominant interfering Bub1 mutant is insufficient to induce or alter thymic tumorigenesis in vivo, even in a sensitized genetic background.
Mol Cell Biol
; 25(17): 7796-802, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16107724