Detalhe da pesquisa
1.
A first-in-human study of the novel metabolism-based anti-cancer agent SM-88 in subjects with advanced metastatic cancer.
Invest New Drugs
; 38(2): 392-401, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30929156
2.
First-in-human study of the anti-HB-EGF antibody U3-1565 in subjects with advanced solid tumors.
Invest New Drugs
; 37(1): 147-158, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30056611
3.
Phase 1 Study To Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Oral Doses of DS-2969b, a Novel GyrB Inhibitor, in Healthy Subjects.
Antimicrob Agents Chemother
; 62(5)2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29439973
4.
Edoxaban effects on bleeding following punch biopsy and reversal by a 4-factor prothrombin complex concentrate.
Circulation
; 131(1): 82-90, 2015 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25403645
5.
Genetics and the clinical response to warfarin and edoxaban: findings from the randomised, double-blind ENGAGE AF-TIMI 48 trial.
Lancet
; 385(9984): 2280-7, 2015 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25769357
6.
Kallikrein 6 is a novel molecular trigger of reactive astrogliosis.
Biol Chem
; 393(5): 355-67, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22505518
7.
Safety and Pharmacokinetics of DS-1040 Drug-Drug Interactions With Aspirin, Clopidogrel, and Enoxaparin.
J Clin Pharmacol
; 60(6): 691-701, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32106339
8.
Protease-activated receptor dependent and independent signaling by kallikreins 1 and 6 in CNS neuron and astroglial cell lines.
J Neurochem
; 107(3): 855-70, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18778305
9.
A Phase I, Single-Ascending-Dose Study in Healthy Subjects to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DS-2969b, a Novel GyrB Inhibitor.
J Clin Pharmacol
; 58(12): 1557-1565, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29746725
10.
A randomized Phase I study of Atuna racemosa: a potential new anti-MRSA natural product extract.
J Ethnopharmacol
; 114(3): 371-6, 2007 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-17889468
11.
Genetics and clinical response to warfarin and edoxaban in patients with venous thromboembolism.
Heart
; 103(22): 1800-1805, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28689179
12.
Low-dosage methotrexate for treatment and maintenance of remission in patients with inflammatory bowel disease.
Pharmacotherapy
; 22(5): 613-20, 2002 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12013360
13.
G protein receptor kinase 4 polymorphisms: ß-blocker pharmacogenetics and treatment-related outcomes in hypertension.
Hypertension
; 60(4): 957-64, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22949529
14.
Functional role of kallikrein 6 in regulating immune cell survival.
PLoS One
; 6(3): e18376, 2011 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21464892
15.
Kallikreins are associated with secondary progressive multiple sclerosis and promote neurodegeneration.
Biol Chem
; 389(6): 739-45, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18627300