Detalhe da pesquisa
1.
A tag-free collisionally induced fragmentation approach to detect drug-adducted proteins by mass spectrometry.
Rapid Commun Mass Spectrom
; 29(22): 2175-83, 2015 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-26467230
2.
Deuterium isotope effects on drug pharmacokinetics. I. System-dependent effects of specific deuteration with aldehyde oxidase cleared drugs.
Drug Metab Dispos
; 40(3): 625-34, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22190693
3.
The use of 18O-exchange and base-catalyzed N-dealkylation with liquid chromatography/tandem mass spectrometry to identify carbinolamide metabolites.
Rapid Commun Mass Spectrom
; 24(14): 2151-61, 2010 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-20552706
4.
A rapid and specific derivatization procedure to identify acyl-glucuronides by mass spectrometry.
Rapid Commun Mass Spectrom
; 24(14): 2109-21, 2010 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-20552710
5.
Deuterium isotope effects in drug pharmacokinetics II: Substrate-dependence of the reaction mechanism influences outcome for cytochrome P450 cleared drugs.
PLoS One
; 13(11): e0206279, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30427871
6.
MT FdR: a ferredoxin reductase from M. tuberculosis that couples to MT CYP51.
Biochim Biophys Acta
; 1707(2-3): 157-69, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-15863094
7.
Metabolic activation of the nontricyclic antidepressant trazodone to electrophilic quinone-imine and epoxide intermediates in human liver microsomes and recombinant P4503A4.
Chem Biol Interact
; 155(1-2): 10-20, 2005 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-15978881
8.
A simple litmus test for aldehyde oxidase metabolism of heteroarenes.
J Med Chem
; 57(4): 1616-20, 2014 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-24472070
9.
Molecular etiology of atherogenesis--in vitro induction of lipidosis in macrophages with a new LDL model.
PLoS One
; 7(4): e34822, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22514671
10.
Discovery of azetidinyl ketolides for the treatment of susceptible and multidrug resistant community-acquired respiratory tract infections.
J Med Chem
; 52(23): 7446-57, 2009 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-19775168
11.
Bioactivation of the nontricyclic antidepressant nefazodone to a reactive quinone-imine species in human liver microsomes and recombinant cytochrome P450 3A4.
Drug Metab Dispos
; 33(2): 243-53, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15523046
12.
In vitro drug interactions of cytochrome p450: an evaluation of fluorogenic to conventional substrates.
Drug Metab Dispos
; 31(8): 1005-15, 2003 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12867489
13.
In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha-cyanoenol metabolite A771726: mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximes.
Drug Metab Dispos
; 31(10): 1240-50, 2003 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12975333
14.
Radical intermediates in peroxide-dependent reactions catalyzed by cytochrome P-450.
J Biosci
; 1987 Mar; 11(1-4): 35-40
Artigo
em Inglês
| IMSEAR | ID: sea-160502