Detalhe da pesquisa
1.
Base editing of key residues in the BCL11A-XL-specific zinc finger domains derepresses fetal globin expression.
Mol Ther
; 32(3): 663-677, 2024 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38273654
2.
Inhibition of NRF2 signaling overcomes acquired resistance to arsenic trioxide in FLT3-mutated Acute Myeloid Leukemia.
Ann Hematol
; 103(6): 1919-1929, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38630133
3.
Comprehensive laboratory diagnosis of Fanconi anaemia: comparison of cellular and molecular analysis.
J Med Genet
; 60(8): 801-809, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36894310
4.
Role of Long Non-Coding RNAs in Human-Induced Pluripotent Stem Cells Derived Megakaryocytes: A p53, HOX Antisense Intergenic RNA Myeloid 1, and miR-125b Interaction Study.
J Pharmacol Exp Ther
; 384(1): 92-101, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36243404
5.
Identification of rare and novel deletions that cause (뫧)0-thalassaemia and hereditary persistence of foetal haemoglobin in Indian population.
Eur J Haematol
; 92(6): 514-20, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24471888
6.
Immortalised chronic myeloid leukemia (CML) derived mesenchymal stromal cells (MSCs) line retains the immunomodulatory and chemoprotective properties of CML patient-derived MSCs.
Cell Signal
; 116: 111067, 2024 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38281615
7.
Establishment and characterization of CSCRi006-A: an induced pluripotent stem cell line generated from a patient with Diamond-Blackfan Anemia (DBA) carrying ribosomal protein S19 (RPS19) mutation.
Hum Cell
; 36(6): 2204-2213, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37603219
8.
Generation and characterization of induced pluripotent stem cell line IITGi001-A derived from adult human primary dermal fibroblasts.
Stem Cell Res
; 71: 103159, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37392703
9.
Efficient gene editing in induced pluripotent stem cells enabled by an inducible adenine base editor with tunable expression.
Sci Rep
; 13(1): 21953, 2023 12 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38081875
10.
Modulating retinoid-X-receptor alpha (RXRA) expression sensitizes chronic myeloid leukemia cells to imatinib in vitro and reduces disease burden in vivo.
Front Pharmacol
; 14: 1187066, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37324449
11.
Editing the core region in HPFH deletions alters fetal and adult globin expression for treatment of ß-hemoglobinopathies.
Mol Ther Nucleic Acids
; 32: 671-688, 2023 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37215154
12.
Efficient deletion of microRNAs using CRISPR/Cas9 with dual guide RNAs.
Front Mol Biosci
; 10: 1295507, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38628442
13.
Gene Editing in Human Induced Pluripotent Stem Cells Using Doxycycline-Inducible CRISPR-Cas9 System.
Methods Mol Biol
; 2454: 755-773, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-33830454
14.
Derivation of Clinical-Grade Induced Pluripotent Stem Cell Lines from Erythroid Progenitor Cells in Xenofree Conditions.
Methods Mol Biol
; 2454: 775-789, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-33950379
15.
Erythroid lineage-specific lentiviral RNAi vectors suitable for molecular functional studies and therapeutic applications.
Sci Rep
; 12(1): 14033, 2022 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35982069
16.
Optimization of SARS-CoV-2 Pseudovirion Production in Lentivirus Backbone With a Novel Liposomal System.
Front Pharmacol
; 13: 840727, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35401169
17.
Efficient and error-free correction of sickle mutation in human erythroid cells using prime editor-2.
Front Genome Ed
; 4: 1085111, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36605051
18.
Preferential Expansion of Human CD34+CD133+CD90+ Hematopoietic Stem Cells Enhances Gene-Modified Cell Frequency for Gene Therapy.
Hum Gene Ther
; 33(3-4): 188-201, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34486377
19.
Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin.
Elife
; 112022 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35147495
20.
Comprehensive Analysis of microRNAs in Human Adult Erythropoiesis.
Cells
; 10(11)2021 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34831239