Detalhe da pesquisa
1.
Small-molecule CFTR activators increase tear secretion and prevent experimental dry eye disease.
FASEB J
; 30(5): 1789-97, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26842854
2.
Inhibitors of pendrin anion exchange identified in a small molecule screen increase airway surface liquid volume in cystic fibrosis.
FASEB J
; 30(6): 2187-97, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26932931
3.
Experimental Evaluation of Proposed Small-Molecule Inhibitors of Water Channel Aquaporin-1.
Mol Pharmacol
; 89(6): 686-93, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26993802
4.
Structure-activity analysis of thiourea analogs as inhibitors of UT-A and UT-B urea transporters.
Biochim Biophys Acta
; 1848(5): 1075-80, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25613743
5.
Aquaporin-1 retards renal cyst development in polycystic kidney disease by inhibition of Wnt signaling.
FASEB J
; 29(4): 1551-63, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25573755
6.
Potentiators of Defective ΔF508-CFTR Gating that Do Not Interfere with Corrector Action.
Mol Pharmacol
; 88(4): 791-9, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26245207
7.
Benzopyrimido-pyrrolo-oxazine-dione (R)-BPO-27 Inhibits CFTR Chloride Channel Gating by Competition with ATP.
Mol Pharmacol
; 88(4): 689-96, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26174774
8.
Aquaporin-4 regulates the velocity and frequency of cortical spreading depression in mice.
Glia
; 63(10): 1860-9, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25944186
9.
Aquaporin-1 gene deletion reduces breast tumor growth and lung metastasis in tumor-producing MMTV-PyVT mice.
FASEB J
; 28(3): 1446-53, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24334548
10.
Greatly improved survival and neuroprotection in aquaporin-4-knockout mice following global cerebral ischemia.
FASEB J
; 28(2): 705-14, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24186965
11.
Diuresis and reduced urinary osmolality in rats produced by small-molecule UT-A-selective urea transport inhibitors.
FASEB J
; 28(9): 3878-90, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24843071
12.
Small molecule screen yields inhibitors of Pseudomonas homoserine lactone-induced host responses.
Cell Microbiol
; 16(1): 1-14, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23910799
13.
Chloride channel inhibition by a red wine extract and a synthetic small molecule prevents rotaviral secretory diarrhoea in neonatal mice.
Gut
; 63(7): 1120-9, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24052273
14.
Protein trafficking rates assessed by quantum dot quenching with bromocresol green.
Traffic
; 13(1): 25-9, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21951589
15.
Post-Golgi supramolecular assembly of aquaporin-4 in orthogonal arrays.
Traffic
; 13(1): 43-53, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21981006
16.
Synergy-based small-molecule screen using a human lung epithelial cell line yields ΔF508-CFTR correctors that augment VX-809 maximal efficacy.
Mol Pharmacol
; 86(1): 42-51, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24737137
17.
Aquaporin-4 deletion in mice reduces encephalopathy and brain edema in experimental acute liver failure.
Neurobiol Dis
; 63: 222-8, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24321433
18.
Aquaporins in clinical medicine.
Annu Rev Med
; 63: 303-16, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22248325
19.
Super-resolution imaging of aquaporin-4 orthogonal arrays of particles in cell membranes.
J Cell Sci
; 125(Pt 18): 4405-12, 2012 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22718347
20.
Discovery and development of antisecretory drugs for treating diarrheal diseases.
Clin Gastroenterol Hepatol
; 12(2): 204-9, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24316107