Detalhe da pesquisa
1.
The impact of inosine on hippocampal synaptic transmission and plasticity involves the release of adenosine through equilibrative nucleoside transporters rather than the direct activation of adenosine receptors.
Purinergic Signal
; 19(2): 451-461, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36156760
2.
Anti-Inflammatory Activities of 8-Benzylaminoxanthines Showing High Adenosine A2A and Dual A1/A2A Receptor Affinity.
Int J Mol Sci
; 24(18)2023 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37762006
3.
Irreversible Antagonists for the Adenosine A2B Receptor.
Molecules
; 27(12)2022 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35744918
4.
Single Stabilizing Point Mutation Enables High-Resolution Co-Crystal Structures of the Adenosine A2A Receptor with Preladenant Conjugates.
Angew Chem Int Ed Engl
; 61(22): e202115545, 2022 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35174942
5.
Targeting the Main Protease of SARS-CoV-2: From the Establishment of High Throughput Screening to the Design of Tailored Inhibitors.
Angew Chem Int Ed Engl
; 60(18): 10423-10429, 2021 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33655614
6.
8-Benzylaminoxanthine scaffold variations for selective ligands acting on adenosine A2A receptors. Design, synthesis and biological evaluation.
Bioorg Chem
; 101: 104033, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32629282
7.
Structural Insights into Partial Activation of the Prototypic G Protein-Coupled Adenosine A2A Receptor.
ACS Pharmacol Transl Sci
; 7(5): 1415-1425, 2024 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38751633
8.
Synthesis of novel pyrido[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives: potent and selective adenosine A3 receptor antagonists.
Arch Pharm (Weinheim)
; 346(10): 699-707, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23996524
9.
Xanthine-Dopamine Hybrid Molecules as Multitarget Drugs with Potential for the Treatment of Neurodegenerative Diseases.
Biomolecules
; 13(7)2023 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37509114
10.
Design, Synthesis and Biological Evaluation of Highly Potent Simplified Archazolids.
ChemMedChem
; 15(14): 1348-1363, 2020 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32363789