Detalhe da pesquisa
1.
Conjugates of adenosine mimetics and arginine-rich peptides serve as inhibitors and fluorescent probes but not as long-lifetime photoluminescent probes for protein arginine methyltransferases.
J Pept Sci
; 29(3): e3456, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36208424
2.
Deactivatable Bisubstrate Inhibitors of Protein Kinases.
Molecules
; 27(19)2022 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36235226
3.
Progesterone triggers Rho kinase-cofilin axis during in vitro and in vivo endometrial decidualization.
Hum Reprod
; 36(8): 2230-2248, 2021 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34270712
4.
Crystal Structure-Guided Design of Bisubstrate Inhibitors and Photoluminescent Probes for Protein Kinases of the PIM Family.
Molecules
; 26(14)2021 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34299628
5.
Unexpected CK2ß-antagonistic functionality of bisubstrate inhibitors targeting protein kinase CK2.
Bioorg Chem
; 96: 103608, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32058103
6.
Thiazole- and selenazole-comprising high-affinity inhibitors possess bright microsecond-scale photoluminescence in complex with protein kinase CK2.
Bioorg Med Chem
; 26(18): 5062-5068, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30217463
7.
Slowly on, Slowly off: Bisubstrate-Analogue Conjugates of 5-Iodotubercidin and Histone H3 Peptide Targeting Protein Kinase Haspin.
Chembiochem
; 18(8): 790-798, 2017 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28181383
8.
Binding assay for characterization of protein kinase inhibitors possessing sub-picomolar to sub-millimolar affinity.
Anal Biochem
; 531: 67-77, 2017 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28527909
9.
Oligo-aspartic acid conjugates with benzo[c][2,6]naphthyridine-8-carboxylic acid scaffold as picomolar inhibitors of CK2.
Bioorg Med Chem
; 25(7): 2277-2284, 2017 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28274673
10.
Acetoxymethyl Ester of Tetrabromobenzimidazole-Peptoid Conjugate for Inhibition of Protein Kinase CK2 in Living Cells.
Bioconjug Chem
; 26(12): 2324-35, 2015 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26559659
11.
FRET-based screening assay using small-molecule photoluminescent probes in lysate of cells overexpressing RFP-fused protein kinases.
Anal Biochem
; 481: 10-7, 2015 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25866074
12.
Responsive microsecond-lifetime photoluminescent probes for analysis of protein kinases and their inhibitors.
Biochim Biophys Acta
; 1834(7): 1330-5, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23499784
13.
Long residence times revealed by Aurora A kinase-targeting fluorescent probes derived from inhibitors MLN8237 and VX-689.
Chembiochem
; 15(3): 443-50, 2014 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24403173
14.
A subnanomolar fluorescent probe for protein kinase CK2 interaction studies.
Org Biomol Chem
; 10(43): 8645-53, 2012 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23032938
15.
Construction of Covalent Bisubstrate Inhibitor of Protein Kinase Reacting with Cysteine Residue at Substrate-Binding Site.
J Med Chem
; 65(16): 10975-10991, 2022 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35960538
16.
Bisubstrate fluorescent probes and biosensors in binding assays for HTS of protein kinase inhibitors.
Biochim Biophys Acta
; 1804(3): 541-6, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19879386
17.
Discovery of strong inhibitory properties of a monoclonal antibody of PKA and use of the antibody and a competitive photoluminescent orthosteric probe for analysis of the protein kinase.
Biochim Biophys Acta Proteins Proteom
; 1868(8): 140427, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32283249
18.
High-affinity bisubstrate probe for fluorescence anisotropy binding/displacement assays with protein kinases PKA and ROCK.
Anal Biochem
; 385(1): 85-93, 2009 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19017524
19.
Efficient photocaging of a tight-binding bisubstrate inhibitor of cAMP-dependent protein kinase.
Chem Commun (Camb)
; 55(74): 11147-11150, 2019 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31464306
20.
A Selective Biligand Inhibitor of CK2 Increases Caspase-3 Activity in Cancer Cells and Inhibits Platelet Aggregation.
ChemMedChem
; 12(20): 1723-1736, 2017 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28837260