Detalhe da pesquisa
1.
Preclinical Characterization of (R)-3-((3S,4S)-3-fluoro-4-(4-hydroxyphenyl)piperidin-1-yl)-1-(4-methylbenzyl)pyrrolidin-2-one (BMS-986169), a Novel, Intravenous, Glutamate N-Methyl-d-Aspartate 2B Receptor Negative Allosteric Modulator with Potential in Major Depressive Disorder.
J Pharmacol Exp Ther
; 363(3): 377-393, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28954811
2.
Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain.
J Pharmacol Exp Ther
; 358(3): 371-86, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27411717
3.
Bacillus Calmette-Guérin vaccine induces a selective serotonin reuptake inhibitor (SSRI)-resistant depression like phenotype in mice.
Brain Behav Immun
; 42: 204-11, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25016199
4.
Role of hepatic blood flow and metabolism in the pharmacokinetics of ten drugs in lean, aged and obese rats.
Xenobiotica
; 44(12): 1108-16, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24947446
5.
Diminished responses to monoaminergic antidepressants but not ketamine in a mouse model for neuropsychiatric lupus.
J Psychopharmacol
; 33(1): 25-36, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30484737
6.
Human aldose reductase expression accelerates diabetic atherosclerosis in transgenic mice.
J Clin Invest
; 115(9): 2434-43, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16127462
7.
BMS-986163, a Negative Allosteric Modulator of GluN2B with Potential Utility in Major Depressive Disorder.
ACS Med Chem Lett
; 9(5): 472-477, 2018 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29795762
8.
[3H]BMT-046091 a potent and selective radioligand to determine AAK1 distribution and target engagement.
Neuropharmacology
; 118: 167-174, 2017 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28315351
9.
Characterization of the adrenocorticotrophic hormone - induced mouse model of resistance to antidepressant drug treatment.
Pharmacol Biochem Behav
; 161: 53-61, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28911960
10.
Insulin sensitizing property of Indigofera mysorensis extract.
J Ethnopharmacol
; 105(1-2): 102-6, 2006 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-16326056
11.
Ragaglitazar: a novel PPAR alpha PPAR gamma agonist with potent lipid-lowering and insulin-sensitizing efficacy in animal models.
Br J Pharmacol
; 140(3): 527-37, 2003 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12970088
12.
Antidiabetic and hypolipidemic potential of DRF 2519--a dual activator of PPAR-alpha and PPAR-gamma.
Eur J Pharmacol
; 491(2-3): 195-206, 2004 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-15140637
13.
Antidiabetic and hypolipidemic activity of Helicteres isora in animal models.
J Ethnopharmacol
; 81(3): 343-9, 2002 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12127235
14.
Therapeutic potential of chloroquine in a murine model of inflammatory bowel disease.
Int Immunopharmacol
; 21(2): 328-35, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24859061
15.
Effects of lipoprotein lipase and statins on cholesterol uptake into heart and skeletal muscle.
J Lipid Res
; 48(3): 646-55, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17189607
16.
Addition of dietary fat to cholesterol in the diets of LDL receptor knockout mice: effects on plasma insulin, lipoproteins, and atherosclerosis.
J Lipid Res
; 47(10): 2215-22, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16840797
17.
Peroxisome proliferator-activated receptor agonists modulate heart function in transgenic mice with lipotoxic cardiomyopathy.
J Pharmacol Exp Ther
; 313(2): 586-93, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15671204
18.
Atherosclerosis in perlecan heterozygous mice.
J Lipid Res
; 45(10): 1806-12, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15258195
19.
DRF 2655: a unique molecule that reduces body weight and ameliorates metabolic abnormalities.
Obes Res
; 11(2): 292-303, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12582227
20.
Inflammatory cytokines and fatty acids regulate endothelial cell heparanase expression.
Biochemistry
; 43(17): 4971-7, 2004 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-15109255