Detalhe da pesquisa
1.
Preclinical Characterization of (R)-3-((3S,4S)-3-fluoro-4-(4-hydroxyphenyl)piperidin-1-yl)-1-(4-methylbenzyl)pyrrolidin-2-one (BMS-986169), a Novel, Intravenous, Glutamate N-Methyl-d-Aspartate 2B Receptor Negative Allosteric Modulator with Potential in Major Depressive Disorder.
J Pharmacol Exp Ther
; 363(3): 377-393, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28954811
2.
Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain.
J Pharmacol Exp Ther
; 358(3): 371-86, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27411717
3.
Role of hepatic blood flow and metabolism in the pharmacokinetics of ten drugs in lean, aged and obese rats.
Xenobiotica
; 44(12): 1108-16, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24947446
4.
Diminished responses to monoaminergic antidepressants but not ketamine in a mouse model for neuropsychiatric lupus.
J Psychopharmacol
; 33(1): 25-36, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30484737
5.
Human aldose reductase expression accelerates diabetic atherosclerosis in transgenic mice.
J Clin Invest
; 115(9): 2434-43, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16127462
6.
[3H]BMT-046091 a potent and selective radioligand to determine AAK1 distribution and target engagement.
Neuropharmacology
; 118: 167-174, 2017 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28315351
7.
Characterization of the adrenocorticotrophic hormone - induced mouse model of resistance to antidepressant drug treatment.
Pharmacol Biochem Behav
; 161: 53-61, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28911960
8.
Insulin sensitizing property of Indigofera mysorensis extract.
J Ethnopharmacol
; 105(1-2): 102-6, 2006 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-16326056
9.
Ragaglitazar: a novel PPAR alpha PPAR gamma agonist with potent lipid-lowering and insulin-sensitizing efficacy in animal models.
Br J Pharmacol
; 140(3): 527-37, 2003 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12970088
10.
Antidiabetic and hypolipidemic potential of DRF 2519--a dual activator of PPAR-alpha and PPAR-gamma.
Eur J Pharmacol
; 491(2-3): 195-206, 2004 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-15140637
11.
Antidiabetic and hypolipidemic activity of Helicteres isora in animal models.
J Ethnopharmacol
; 81(3): 343-9, 2002 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12127235
12.
Effects of lipoprotein lipase and statins on cholesterol uptake into heart and skeletal muscle.
J Lipid Res
; 48(3): 646-55, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17189607
13.
Peroxisome proliferator-activated receptor agonists modulate heart function in transgenic mice with lipotoxic cardiomyopathy.
J Pharmacol Exp Ther
; 313(2): 586-93, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15671204
14.
Atherosclerosis in perlecan heterozygous mice.
J Lipid Res
; 45(10): 1806-12, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15258195
15.
DRF 2655: a unique molecule that reduces body weight and ameliorates metabolic abnormalities.
Obes Res
; 11(2): 292-303, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12582227
16.
Cardiac-specific knock-out of lipoprotein lipase alters plasma lipoprotein triglyceride metabolism and cardiac gene expression.
J Biol Chem
; 279(24): 25050-7, 2004 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-15028738
17.
PAT5A: a partial agonist of peroxisome proliferator-activated receptor gamma is a potent antidiabetic thiazolidinedione yet weakly adipogenic.
J Pharmacol Exp Ther
; 306(2): 763-71, 2003 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12730351
18.
Synthesis and biological activity of novel pyrimidinone containing thiazolidinedione derivatives.
Bioorg Med Chem
; 10(8): 2671-80, 2002 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12057656