Detalhe da pesquisa
1.
Anxiety, depression, and memory loss in Chagas disease: a puzzle far beyond neuroinflammation to be unpicked and solved.
Mem Inst Oswaldo Cruz
; 118: e220287, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37018799
2.
Resveratrol Reverses Functional Chagas Heart Disease in Mice.
PLoS Pathog
; 12(10): e1005947, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27788262
3.
A human type 5 adenovirus-based Trypanosoma cruzi therapeutic vaccine re-programs immune response and reverses chronic cardiomyopathy.
PLoS Pathog
; 11(1): e1004594, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25617628
4.
Combination Chemotherapy with Suboptimal Doses of Benznidazole and Pentoxifylline Sustains Partial Reversion of Experimental Chagas' Heart Disease.
Antimicrob Agents Chemother
; 60(7): 4297-309, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27161638
5.
Behavioural alterations are independent of sickness behaviour in chronic experimental Chagas disease.
Mem Inst Oswaldo Cruz
; 110(8): 1042-50, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26676323
6.
Levels of circulating anti-muscarinic and anti-adrenergic antibodies and their effect on cardiac arrhythmias and dysautonomia in murine models of Chagas disease.
Parasitology
; 141(13): 1769-78, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25093253
7.
Tumor necrosis factor is a therapeutic target for immunological unbalance and cardiac abnormalities in chronic experimental Chagas' heart disease.
Mediators Inflamm
; 2014: 798078, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25140115
8.
Severity of chronic experimental Chagas' heart disease parallels tumour necrosis factor and nitric oxide levels in the serum: models of mild and severe disease.
Mem Inst Oswaldo Cruz
; 109(3): 289-98, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24937048
9.
Preclinical evaluation of combined therapy with amiodarone and low-dose benznidazole in a mouse model of chronic Trypanosoma cruzi infection.
Biomed Pharmacother
; 175: 116742, 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38754265
10.
The beneficial effect of fluoxetine on behavioral and cognitive changes in chronic experimental Chagas disease unveils the role of serotonin fueling astrocyte infection by Trypanosoma cruzi.
PLoS Negl Trop Dis
; 18(5): e0012199, 2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38776344
11.
Treatment with benznidazole and pentoxifylline regulates microRNA transcriptomic profile in a murine model of Chagas chronic cardiomyopathy.
PLoS Negl Trop Dis
; 17(3): e0011223, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36972298
12.
Genetic Ablation and Pharmacological Blockade of Bradykinin B1 Receptor Unveiled a Detrimental Role for the Kinin System in Chagas Disease Cardiomyopathy.
J Clin Med
; 12(8)2023 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37109224
13.
Trypanosoma cruzi-induced depressive-like behavior is independent of meningoencephalitis but responsive to parasiticide and TNF-targeted therapeutic interventions.
Brain Behav Immun
; 26(7): 1136-49, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22841695
14.
In Chagas disease, transforming growth factor beta neutralization reduces Trypanosoma cruzi infection and improves cardiac performance.
Front Cell Infect Microbiol
; 12: 1017040, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36530434
15.
Treatment With Suboptimal Dose of Benznidazole Mitigates Immune Response Molecular Pathways in Mice With Chronic Chagas Cardiomyopathy.
Front Cell Infect Microbiol
; 11: 692655, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34381739
16.
Memory impairment in chronic experimental Chagas disease: Benznidazole therapy reversed cognitive deficit in association with reduction of parasite load and oxidative stress in the nervous tissue.
PLoS One
; 16(1): e0244710, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33400707
17.
Physical Exercise Promotes a Reduction in Cardiac Fibrosis in the Chronic Indeterminate Form of Experimental Chagas Disease.
Front Immunol
; 12: 712034, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34804007
18.
CCL3/Macrophage Inflammatory Protein-1α Is Dually Involved in Parasite Persistence and Induction of a TNF- and IFNγ-Enriched Inflammatory Milieu in Trypanosoma cruzi-Induced Chronic Cardiomyopathy.
Front Immunol
; 11: 306, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32194558
19.
TGF-ß inhibitor therapy decreases fibrosis and stimulates cardiac improvement in a pre-clinical study of chronic Chagas' heart disease.
PLoS Negl Trop Dis
; 13(7): e0007602, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31365537
20.
Anxiety, depression, and memory loss in Chagas disease: a puzzle far beyond neuroinflammation to be unpicked and solved*
Mem. Inst. Oswaldo Cruz
; 118: e220287, 2023. graf
Artigo
em Inglês
|
LILACS-Express
| ID: biblio-1430843