Long-term outcomes of the global tuberculosis and COVID-19 co-infection cohort.

BACKGROUND: Longitudinal cohort data of patients with tuberculosis (TB) and coronavirus disease 2019 (COVID-19) are lacking. In our global study, we describe long-term outcomes of patients affected by TB and COVID-19. METHODS: We collected data from 174 centres in 31 countries on all patients affected by COVID-19 and TB between 1 March 2020 and 30 September 2022. Patients were followed-up until cure, death or end of cohort time. All patients had TB and COVID-19; for analysis purposes, deaths were attributed to TB, COVID-19 or both. Survival analysis was performed using Cox proportional risk-regression models, and the log-rank test was used to compare survival and mortality attributed to TB, COVID-19 or both. RESULTS: Overall, 788 patients with COVID-19 and TB (active or sequelae) were recruited from 31 countries, and 10.8% (n=85) died during the observation period. Survival was significantly lower among patients whose death was attributed to TB and COVID-19 versus those dying because of either TB or COVID-19 alone (p<0.001). Significant adjusted risk factors for TB mortality were higher age (hazard ratio (HR) 1.05, 95% CI 1.03-1.07), HIV infection (HR 2.29, 95% CI 1.02-5.16) and invasive ventilation (HR 4.28, 95% CI 2.34-7.83). For COVID-19 mortality, the adjusted risks were higher age (HR 1.03, 95% CI 1.02-1.04), male sex (HR 2.21, 95% CI 1.24-3.91), oxygen requirement (HR 7.93, 95% CI 3.44-18.26) and invasive ventilation (HR 2.19, 95% CI 1.36-3.53). CONCLUSIONS: In our global cohort, death was the outcome in >10% of patients with TB and COVID-19. A range of demographic and clinical predictors are associated with adverse outcomes.

[Validation of a questionnaire that measures perceptions of the role of community nursing professionals in Peru]. / Validación de un cuestionario que mide las percepciones del rol del profesional de enfermería comunitaria en Perú.

OBJECTIVE: To develop a valid and reliable scale to measure the role of the nursing professional in the community (REFCO). DESIGN: Observational with cross-sectional and instrumental design. SITE: Populated centers and communities of the coast, highlands and jungle from Peru. PARTICIPANTS: The validation phase of the questionnaire had the voluntary participation of 402 Peruvian adults (50.7% from the coast, 40.5% from the highlands and 8.8% from the jungle). INTERVENTIONS: The elaborated questionnaire that measures perceptions about the role of the nursing professional in the community was applied. MAIN MEASUREMENTS: The psychometric properties of the REFCO scale were analyzed, such as content validation and internal consistency through the calculation of Aiken's V, exploratory factor analysis (EFA) and later confirmatory factor analysis (CFA), respectively. Finally, the reliability of the scale was calculated. RESULTS: Overall, all values were statistically significant when evaluated with the V-Aiken coefficient. Likewise, the skewness and kurtosis values of all the items of the instrument did not exceed the range >±1.5. The correlations between factors 1 and 2 were significant (p < .05). The reliability of the scale presents a Cronbach's α coefficient = 0.865. CONCLUSIONS: The REFCO scale has 9 items and 2 dimensions; outreach and education; with content and construct validity that provide evidence for community nursing categories, which is useful for measuring nursing work in the community field.

Validación de un cuestionario que mide las percepciones del rol del profesional de enfermería comunitaria en Perú / Validation of a questionnaire that measures perceptions of the role of community nursing professionals in Peru

Objetivo: Elaborar una escala válida y fiable para medir el rol del profesional de enfermería en la comunidad (REFCO).DiseñoEstudio observacional con diseño transversal de tipo instrumental.EmplazamientoCentros poblados y comunidades de la Costa, Sierra y Selva del Perú.ParticipantesLa fase de validación del cuestionario contó con la participación voluntaria de 402 adultos peruanos (50,7% de la costa, 40,5% de la sierra y 8,8% de la selva).IntervencionesSe aplicó el cuestionario elaborado que mide las percepciones sobre la escala REFCO.Mediciones principalesSe analizaron las propiedades psicométricas de la escala REFCO, tales como la validación de contenido y consistencia interna a través del cálculo de V de Aiken, análisis factorial exploratorio (AFE) y posteriormente análisis factorial confirmatorio (AFC), respectivamente. Finalmente, se calculó la confiabilidad de la escala.ResultadosTodos los valores fueron estadísticamente significativos cuando se evaluaron con el coeficiente de V-Aiken. Asimismo, los valores de asimetría y curtosis de todos los ítems del instrumento no exceden el rango > ± 1,5. Las correlaciones entre el factor 1 y 2 fueron significativas (p <,05). La confiabilidad de la escala presenta un coeficiente α de Cronbach = 0,865.ConclusionesLa escala REFCO posee nueve ítems y dos dimensiones, salida al campo y educación, con validez de contenido y constructo que proporcionan evidencia para categorías de enfermería comunitaria, siendo útil para medir la labor de la misma en el campo comunitario.

Objective: To develop a valid and reliable scale to measure the role of the nursing professional in the community (REFCO).DesignObservational with cross-sectional and instrumental design.SitePopulated centers and communities of the coast, highlands and jungle from Peru.ParticipantsThe validation phase of the questionnaire had the voluntary participation of 402 Peruvian adults (50.7% from the coast, 40.5% from the highlands and 8.8% from the jungle).InterventionsThe elaborated questionnaire that measures perceptions about the role of the nursing professional in the community was applied.Main measurementsThe psychometric properties of the REFCO scale were analyzed, such as content validation and internal consistency through the calculation of Aiken's V, exploratory factor analysis (EFA) and later confirmatory factor analysis (CFA), respectively. Finally, the reliability of the scale was calculated.ResultsOverall, all values were statistically significant when evaluated with the V-Aiken coefficient. Likewise, the skewness and kurtosis values of all the items of the instrument did not exceed the range >±1.5. The correlations between factors 1 and 2 were significant (p < .05). The reliability of the scale presents a Cronbach's α coefficient = 0.865.ConclusionsThe REFCO scale has 9 items and 2 dimensions; outreach and education; with content and construct validity that provide evidence for community nursing categories, which is useful for measuring nursing work in the community field.