Detalhe da pesquisa
1.
Molecular dynamics simulations of the calmodulin-induced α-helix in the SK2 calcium-gated potassium ion channel.
J Biol Chem
; 299(2): 102850, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36587765
2.
MLe-KCNQ2: An Artificial Intelligence Model for the Prognosis of Missense KCNQ2 Gene Variants.
Int J Mol Sci
; 25(5)2024 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38474157
3.
An epilepsy-causing mutation leads to co-translational misfolding of the Kv7.2 channel.
BMC Biol
; 19(1): 109, 2021 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34020651
4.
Structural basis and energy landscape for the Ca2+ gating and calmodulation of the Kv7.2 K+ channel.
Proc Natl Acad Sci U S A
; 115(10): 2395-2400, 2018 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29463698
5.
Atomistic Insights of Calmodulin Gating of Complete Ion Channels.
Int J Mol Sci
; 21(4)2020 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32075037
6.
Novel Dominant KCNQ2 Exon 7 Partial In-Frame Duplication in a Complex Epileptic and Neurodevelopmental Delay Syndrome.
Int J Mol Sci
; 21(12)2020 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32585800
7.
Homomeric Kv7.2 current suppression is a common feature in KCNQ2 epileptic encephalopathy.
Epilepsia
; 60(1): 139-148, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30478917
8.
The Crossroad of Ion Channels and Calmodulin in Disease.
Int J Mol Sci
; 20(2)2019 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30669290
9.
Ubiquitin-specific Protease 36 (USP36) Controls Neuronal Precursor Cell-expressed Developmentally Down-regulated 4-2 (Nedd4-2) Actions over the Neurotrophin Receptor TrkA and Potassium Voltage-gated Channels 7.2/3 (Kv7.2/3).
J Biol Chem
; 291(36): 19132-45, 2016 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27445338
10.
Uncoupling PIP2-calmodulin regulation of Kv7.2 channels by an assembly destabilizing epileptogenic mutation.
J Cell Sci
; 128(21): 4014-23, 2015 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26359296
11.
An unconventional calmodulin-anchoring site within the AB module of Kv7.2 channels.
J Cell Sci
; 128(16): 3155-63, 2015 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26148514
12.
Epilepsy-causing mutations in Kv7.2 C-terminus affect binding and functional modulation by calmodulin.
Biochim Biophys Acta
; 1852(9): 1856-66, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26073431
13.
Cooperativity between calmodulin-binding sites in Kv7.2 channels.
J Cell Sci
; 126(Pt 1): 244-53, 2013 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23203804
14.
Functional assembly of Kv7.1/Kv7.5 channels with emerging properties on vascular muscle physiology.
Arterioscler Thromb Vasc Biol
; 34(7): 1522-30, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24855057
15.
The neuronal serum- and glucocorticoid-regulated kinase 1.1 reduces neuronal excitability and protects against seizures through upregulation of the M-current.
J Neurosci
; 33(6): 2684-96, 2013 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23392695
16.
Clicked bis-PEG-peptide conjugates for studying calmodulin-Kv7.2 channel binding.
Org Biomol Chem
; 12(44): 8877-87, 2014 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25264745
17.
Fluorometric Measurement of Calmodulin-Dependent Peptide-Protein Interactions Using Dansylated Calmodulin.
Bio Protoc
; 14(7): e4963, 2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38618173
18.
Identification of Riluzole derivatives as novel calmodulin inhibitors with neuroprotective activity by a joint synthesis, biosensor, and computational guided strategy.
Biomed Pharmacother
; 174: 116602, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38636396
19.
The Kv7.2/Kv7.3 heterotetramer assembles with a random subunit arrangement.
J Biol Chem
; 287(15): 11870-7, 2012 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22334706
20.
Redox regulation of KV7 channels through EF3 hand of calmodulin.
Elife
; 122023 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36803414