Compliance with the 2009 Royal College of Obstetricians and Gynaecologists guidelines for venous thromboembolic disease prophylaxis in pregnancy and postpartum period in Uruguay.

: Venous thromboembolism remains as one of the leading causes of maternal death. Prevention of venous thromboembolism in the obstetric population is challenging as recommendations for prophylaxis have low grade of evidence. Risk factors and prophylaxis guidelines have been highlighted by Royal College of Obstetricians and Gynaecologists. In 2014, we developed a written alert following this guidelines to guide thromboprophylaxis. The aim of this study is to assess recommendations compliance. This study was conducted at University-Hospital in Uruguay from January 2014 to December 2016. A total of 1035 women were enrolled and stratified in high, intermediate or low risk based on Royal College of Obstetricians and Gynaecologists guidelines. Thromboprophylaxis was recommended for women at intermediate and high risk. Women were followed up to assess symptomatic thromboembolism or haemorrhagic complications. A total of 309 were pregnant and 731 puerperal. Median age was 24 (19-29) years old. Of them, 3.0% (n = 31) were at high risk and 35.4% (n = 366) at intermediate risk. All high-risk women received prophylaxis with low-molecular-weight heparin. Of the 366 intermediate-risk women, 52.7% received prophylaxis. Venous thromboembolism was developed in only one woman of the intermediate group, who had received prophylaxis. Bleeding complications were not observed. Awareness of the thrombotic risk, as conferred by an easy and suitable risk assessment, has the potential to improve venous thromboembolism prophylaxis in pregnant and puerperal women. We have a good guidelines compliance with the written alert in the high-risk women group. However, we have to improve low-molecular-weight heparin indication in intermediate-risk group, especially in postcaesarean women.

Tertiary-level study of the implementation of a technique checklist for cesarean deliveries at a university hospital in Uruguay.

OBJECTIVE: To assess the adherence of healthcare providers to cesarean-delivery techniques before and after the introduction of a technique checklist at a university hospital. METHODS: A retrospective cross-sectional cohort study included data from all cesarean deliveries at Gynecology Clinic B of the University of the Republic, Montevideo, Uruguay, between January 1 and December 31, 2011. The data were grouped based on whether delivery occurred before or after the implementation of the checklist and were compared across a range of cesarean-delivery techniques. RESULTS: Data from 296 cesarean deliveries were included; 130 from before implementation and 166 from after. After the implementation of the checklist, complete adherence to all techniques was observed in 28 (16.9%) deliveries. Following the introduction of the checklist, the odds of prophylactic cefazolin (OR 8.35, 95% CI 3.74-20.9), chlorhexidine (OR 8.98, 95% CI 3.72-23.7), cord traction for the third stage of labor (OR 2.26, 95% CI 1.33-3.85), and double-layer hysterorrhaphy (OR 3.65, 95% CI 2.09-6.55) being properly applied increased compared with before the implementation of the checklist. CONCLUSIONS: Overall adherence to the prescribed techniques was low. The implementation of this checklist improved the odds of several techniques being applied by between two- and eight-fold.

Asesoramiento anticoncepcional para mujeres con trombofilia hereditaria / Contraception counseling for women with inherited thrombophilia / Aconselhamento de contracepção para mulheres com trombofilia hereditária

Resumen: La anticoncepción en las pacientes con trombofilia es un desafío para el equipo de salud. La función de asesoramiento en materia de planificación familiar va más allá de la simple prescripción, ya que para definir el mejor método anticonceptivo no es suficiente la consideración de los antecedentes médicos y obstétricos de la mujer, sino que es imprescindible considerar las preferencias de la paciente. El asesoramiento sobre anticoncepción en las mujeres con trombofilia hereditaria debe abordar los riesgos de enfermedad tromboembólica venosa, incrementada en este grupo de pacientes, considerando cada uno de los métodos anticonceptivos, así como los de un embarazo no buscado, con el objetivo de contribuir a que la decisión se tome de manera informada. La presente revisión aborda este riesgo según cada tipo anticonceptivo en pacientes con distintos tipos de trombofilia hereditaria.

Abstract: Contraception in patients with thrombophilia is a challenge for the health team. The role of family planning counseling goes beyond simple prescription, since in order to define the best contraceptive method, it is not enough to consider the woman's medical and obstetric history, but rather it is essential to consider the patient's preferences . Counseling on contraception in women with hereditary thrombophilia should address the risks of venous thromboembolic disease, increased in this group of patients, considering each of the contraceptive methods, as well as those of an unintended pregnancy, in order to contribute to the the decision is made in an informed manner. The present review addresses this risk according to each contraceptive type in patients with different types of inherited thrombophilia.

Resumo: A contracepção em pacientes com trombofilia é um desafio para a equipe de saúde. O papel do aconselhamento de planejamento familiar vai além da simples prescrição, pois para definir o melhor método anticoncepcional não basta considerar a história médica e obstétrica da mulher, mas sim considerar as preferências da paciente. O aconselhamento sobre contracepção em mulheres com trombofilia hereditária deve abordar os riscos de doença tromboembólica venosa, aumentados neste grupo de pacientes, considerando cada um dos métodos contraceptivos, bem como os de gravidez indesejada, a fim de contribuir para a tomada de decisão de uma forma informada. A presente revisão aborda esse risco de acordo com cada tipo de contraceptivo em pacientes com diferentes tipos de trombofilia hereditária.

Sarcoma sinovial monofásico pulmonar en paciente embarazada: reporte de caso clínico / Monophasic pulmonary synovial sarcoma in pregnant patient: case report

El cáncer durante el embarazo presenta una baja incidencia (0,06-0,1% de todos los embarazos), pero representa un gran dilema diagnóstico y terapéutico. El sarcoma sinovial monofásico pulmonar primario por su parte es muy poco frecuente (constituyendo el 0,1-0,5% de todas las neoplasias de pulmón), siendo aún más rara su presentación en una mujer embarazada como es el caso clínico a presentar. Se trata de una paciente de 21 años con diagnóstico incidental de la neoplasia maligna pulmonar mencionada, diagnosticada durante el embarazo, cuyo tratamiento fue realizado de forma multidisciplinaria y con un plan terapéutico a base de cirugía y poliquimioterapia(AU)

A pilot randomized controlled trial of controlled cord traction to reduce postpartum blood loss.

OBJECTIVE: To evaluate whether controlled cord traction (CCT) for management of the third stage of labor reduced postpartum blood loss compared with a "hands-off" management protocol. METHODS: Women with imminent vaginal delivery were randomly assigned to either a CCT group or a hands-off group. The women received prophylactic oxytocin. The primary outcome was blood loss during the third stage of labor. RESULTS: In total, 103 women were allocated to the CCT group and 101 were allocated to the hands-off group. Median blood loss in the CCT group and the hands-off group was 282.0 mL and 310.2 mL, respectively. The difference in blood loss (-28.2 mL) was not significant (95% confidence interval, -92.3 to 35.9; P=0.126). Blood collection in the hands-off group took 1.2 minutes longer than in the CCT group, which may have contributed to this difference. CONCLUSION: CCT may reduce postpartum blood loss. The present findings support conducting a large trial to determine whether CCT can prevent postpartum hemorrhage.