Detalhe da pesquisa
1.
First-in-human study of alpibectir (BVL-GSK098), a novel potent anti-TB drug.
J Antimicrob Chemother
; 2024 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38656557
2.
Assessment of the safety, pharmacokinetics and pharmacodynamics of GSK3335065, an inhibitor of kynurenine monooxygenase, in a randomised placebo-controlled first-in-human study in healthy volunteers.
Br J Clin Pharmacol
; 88(2): 865-870, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34327739
3.
Target engagement and cellular fate of otelixizumab: a repeat dose escalation study of an anti-CD3ε mAb in new-onset type 1 diabetes mellitus patients.
Br J Clin Pharmacol
; 85(4): 704-714, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30566758
4.
Clinical assessment of momelotinib drug-drug interactions via CYP3A metabolism and transporters.
Clin Transl Sci
; 17(4): e13799, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38634429
5.
A first-in-class leucyl-tRNA synthetase inhibitor, ganfeborole, for rifampicin-susceptible tuberculosis: a phase 2a open-label, randomized trial.
Nat Med
; 30(3): 896-904, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38365949
6.
Machine Learning and Pharmacometrics for Prediction of Pharmacokinetic Data: Differences, Similarities and Challenges Illustrated with Rifampicin.
Pharmaceutics
; 14(8)2022 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35893785
7.
Comparison of 8 weeks standard treatment (rifampicin plus clarithromycin) vs. 4 weeks standard plus amoxicillin/clavulanate treatment [RC8 vs. RCA4] to shorten Buruli ulcer disease therapy (the BLMs4BU trial): study protocol for a randomized controlled multi-centre trial in Benin.
Trials
; 23(1): 559, 2022 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35804454
8.
Bayesian hierarchical methods to interpret the (13)C-octanoic acid breath test for gastric emptying.
Digestion
; 83(1-2): 96-107, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21042021
9.
Randomized 52-week Phase 2 Trial of Albiglutide Versus Placebo in Adult Patients With Newly Diagnosed Type 1 Diabetes.
J Clin Endocrinol Metab
; 105(6)2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32219329
10.
Efficacy and safety of an albiglutide liquid formulation compared with the lyophilized formulation: A 26-week randomized, double-blind, repeat-dose study in patients with type 2 diabetes mellitus.
Diabetes Res Clin Pract
; 152: 125-134, 2019 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-31004676
11.
A Randomized, Double-Blind, Single-Dose, Crossover Study to Demonstrate the Bioequivalence of 2 Formulations of Albiglutide in Healthy Adult Participants.
Clin Pharmacol Drug Dev
; 8(3): 361-370, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30063297
12.
Pharmacokinetics and Tolerability of Exenatide Delivered by 7-Day Continuous Subcutaneous Infusion in Healthy Volunteers.
Adv Ther
; 32(7): 650-61, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26160357