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1.
Am J Ther ; 20(5): 554-7, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-21326086

RESUMO

We present the case of a 12-year-old girl with abnormal extrapyramidal movements associated with basal ganglia lesions after electrical injury. After her injury, our patient initially did well and recovered from acute cardiovascular and hemodynamic instability, and the results of her neurological examination, head computed tomography scan, and electroencephalogram were normal on discharge from hospital. Two weeks after discharge, she developed extrapyramidal movements, and head magnetic resonance imaging showed areas of bilateral, symmetrical enhanced associated with signal intensity in the basal ganglia, hypoxic encephalopathy, and cerebral edema that may have occurred secondary to the cardiopulmonary arrest that she suffered immediately after her accident. The symptoms disappeared after low dose levodopa was instituted and have not recurred during the 15 months of treatment. Injury and death from electric current, although rare, are not uncommon and occur mostly as a result of accidental contact with a live wire. This is the first case report documenting the use of levodopa for extrapyramidal movements secondary to high-tension electrocution.


Assuntos
Doenças dos Gânglios da Base/tratamento farmacológico , Doenças dos Gânglios da Base/etiologia , Traumatismos por Eletricidade/complicações , Parada Cardíaca/complicações , Levodopa/uso terapêutico , Gânglios da Base/lesões , Criança , Eletroencefalografia , Feminino , Humanos , Tomografia Computadorizada por Raios X
2.
Am J Ther ; 18(6): e271-3, 2011 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-20543664

RESUMO

Increase in use of atypical antipsychotics has been paralleled by an increase in the incidence of intentional and nonintentional overdose. Pediatric cases are uncommon, but may be severe. We describe a case of a child presenting with severe extrapiramidal symptoms, initially interpreted as seizures, caused by a nonintentional intoxication with risperidone, and review management options and the literature.


Assuntos
Antipsicóticos/intoxicação , Doenças dos Gânglios da Base/induzido quimicamente , Risperidona/intoxicação , Pré-Escolar , Humanos , Masculino
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