Detalhe da pesquisa
1.
Antibody-mediated activation of the FGFR1/Klothoß complex corrects metabolic dysfunction and alters food preference in obese humans.
Proc Natl Acad Sci U S A
; 117(46): 28992-29000, 2020 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33139537
2.
Randomized Phase II Trial of Parsatuzumab (Anti-EGFL7) or Placebo in Combination with Carboplatin, Paclitaxel, and Bevacizumab for First-Line Nonsquamous Non-Small Cell Lung Cancer.
Oncologist
; 23(6): 654-e58, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29438092
3.
Randomized Phase II Trial of Parsatuzumab (Anti-EGFL7) or Placebo in Combination with FOLFOX and Bevacizumab for First-Line Metastatic Colorectal Cancer.
Oncologist
; 22(4): 375-e30, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28275117
4.
Comparison of binding characteristics and in vitro activities of three inhibitors of vascular endothelial growth factor A.
Mol Pharm
; 11(10): 3421-30, 2014 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25162961
5.
Aqueous humour interleukin-6 and vision outcomes with anti-vascular endothelial growth factor therapy.
Eye (Lond)
; 2024 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38622330
6.
T-cell dependent immunogenicity of protein therapeutics: Preclinical assessment and mitigation.
Clin Immunol
; 149(3): 534-55, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24263283
7.
Randomized Phase II Trial of Parsatuzumab (Anti-EGFL7) or Placebo in Combination with FOLFOX and Bevacizumab for First-Line Metastatic Colorectal Cancer.
Oncologist
; 22(10): 1281, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29018169
8.
Association of endogenous anti-interferon-α autoantibodies with decreased interferon-pathway and disease activity in patients with systemic lupus erythematosus.
Arthritis Rheum
; 63(8): 2407-15, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21506093
9.
Development of an anti-drug antibody assay to detect anti-drug antibodies to protein and PEG in a PEGylated molecule.
Bioanalysis
; 12(23): 1671-1679, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33179526
10.
Immunoaffinity LC-MS/MS is more suitable than ELISA to quantify a PEGylated molecule in cynomolgus monkey serum.
Bioanalysis
; 12(15): 1061-1069, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32735119
11.
Bioanalytical challenges and unique considerations to support pharmacokinetic characterization of bispecific biotherapeutics.
Bioanalysis
; 11(5): 427-435, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30887822
12.
Immunoaffinity LC-MS/MS to quantify a PEGylated anti-Factor D Fab biotherapeutic in cynomolgus monkey serum.
Bioanalysis
; 11(23): 2161-2173, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31701759
13.
Rapid Development of Glaucoma Via ITV Nonselective ANGPT 1/2 Antibody: A Potential Role for ANGPT/TIE2 Signaling in Primate Aqueous Humor Outflow.
Invest Ophthalmol Vis Sci
; 60(13): 4097-4108, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31574535
14.
Increased plasma concentrations of cytoskeletal and Ca2+-binding proteins and their peptides in psoriasis patients.
Clin Chem
; 54(11): 1805-14, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18801941
15.
Development and validation of a novel semi-homogenous clinical assay for quantitation of Ranibizumab in human serum.
J Immunol Methods
; 461: 44-52, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29772250
16.
Phase I study of the anti-α5ß1 monoclonal antibody MINT1526A with or without bevacizumab in patients with advanced solid tumors.
Cancer Chemother Pharmacol
; 82(2): 339-351, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29905898
17.
Recommendations for the design, optimization, and qualification of cell-based assays used for the detection of neutralizing antibody responses elicited to biological therapeutics.
J Immunol Methods
; 321(1-2): 1-18, 2007 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-17307199
18.
Advancements in Understanding Immunogenicity of Biotherapeutics in the Intraocular Space.
AAPS J
; 19(6): 1656-1668, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28795351
19.
Preexisting Antibodies to an F(ab')2 Antibody Therapeutic and Novel Method for Immunogenicity Assessment.
J Immunol Res
; 2016: 2921758, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27413757
20.
Fit-for-purpose biomarker immunoassay qualification and validation: three case studies.
Bioanalysis
; 8(22): 2329-2340, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27712082