Detalhe da pesquisa
1.
A Bispecific Monoclonal Antibody Targeting Psl and PcrV Enhances Neutrophil-Mediated Killing of Pseudomonas aeruginosa in Patients with Bronchiectasis.
Am J Respir Crit Care Med
; 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38754132
2.
Antibacterial Monoclonal Antibodies Do Not Disrupt the Intestinal Microbiome or Its Function.
Antimicrob Agents Chemother
; 64(5)2020 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32152087
3.
A neutralizing antibody that blocks delivery of the enzymatic cargo of Clostridium difficile toxin TcdB into host cells.
J Biol Chem
; 293(3): 941-952, 2018 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29180448
4.
The Neutrophilic Response to Pseudomonas Damages the Airway Barrier, Promoting Infection by Klebsiella pneumoniae.
Am J Respir Cell Mol Biol
; 59(6): 745-756, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30109945
5.
Use of a neutralizing antibody helps identify structural features critical for binding of Clostridium difficile toxin TcdA to the host cell surface.
J Biol Chem
; 292(35): 14401-14412, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28705932
6.
Pseudomonas aeruginosa Bacteremic Patients Exhibit Nonprotective Antibody Titers Against Therapeutic Antibody Targets PcrV and Psl Exopolysaccharide.
J Infect Dis
; 213(4): 640-8, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26333940
7.
A novel anti-PcrV antibody providing enhanced protection against Pseudomonas aeruginosa in multiple animal infection models.
Antimicrob Agents Chemother
; 58(8): 4384-91, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24841258
8.
Synthetic lethality of PARP inhibition in BRCA-network disrupted tumor cells is associated with interferon pathway activation and enhanced by interferon-γ.
Apoptosis
; 17(7): 691-701, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22392482
9.
Phenotypic whole-cell screening identifies a protective carbohydrate epitope on Klebsiella pneumoniae.
MAbs
; 14(1): 2006123, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34923908
10.
Engraftment of Bacteria after Fecal Microbiota Transplantation Is Dependent on Both Frequency of Dosing and Duration of Preparative Antibiotic Regimen.
Microorganisms
; 9(7)2021 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34209573
11.
RNA interference-mediated silencing of mitotic kinesin KIF14 disrupts cell cycle progression and induces cytokinesis failure.
Mol Cell Biol
; 26(10): 3853-63, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16648480
12.
Small interfering RNA screens reveal enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions.
Mol Cell Biol
; 26(24): 9377-86, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17000754
13.
Neutrophil Extracellular Traps Confine Pseudomonas aeruginosa Ocular Biofilms and Restrict Brain Invasion.
Cell Host Microbe
; 25(4): 526-536.e4, 2019 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30930127
14.
Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source.
World J Gastroenterol
; 25(33): 4904-4920, 2019 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31543682
15.
Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors.
MAbs
; 10(1): 104-117, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28952876
16.
Bispecific antibody targets multiple Pseudomonas aeruginosa evasion mechanisms in the lung vasculature.
J Clin Invest
; 127(6): 2249-2261, 2017 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28463232
17.
Anti-LPS antibodies protect against Klebsiella pneumoniae by empowering neutrophil-mediated clearance without neutralizing TLR4.
JCI Insight
; 2(9)2017 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28469079
18.
Immune stealth-driven O2 serotype prevalence and potential for therapeutic antibodies against multidrug resistant Klebsiella pneumoniae.
Nat Commun
; 8(1): 1991, 2017 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29222409
19.
Complement C5a induces PD-L1 expression and acts in synergy with LPS through Erk1/2 and JNK signaling pathways.
Sci Rep
; 6: 33346, 2016 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27624143
20.
Differential expression and roles of Staphylococcus aureus virulence determinants during colonization and disease.
mBio
; 6(1): e02272-14, 2015 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25691592