Detalhe da pesquisa
1.
Crystal structure of the human PRMT5:MEP50 complex.
Proc Natl Acad Sci U S A
; 109(44): 17960-5, 2012 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23071334
2.
Atomic structure of the nuclear pore complex targeting domain of a Nup116 homologue from the yeast, Candida glabrata.
Proteins
; 80(8): 2110-6, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22544723
3.
Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of the RB1 Tumor Suppressor Gene.
Cancer Discov
; 9(2): 248-263, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30373917
4.
Structure of the C-terminal domain of Saccharomyces cerevisiae Nup133, a component of the nuclear pore complex.
Proteins
; 79(5): 1672-7, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21365675
5.
Discovery of (1S,2R,3S,4S,5R,6R)-2-Amino-3-[(3,4-difluorophenyl)sulfanylmethyl]-4-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid Hydrochloride (LY3020371·HCl): A Potent, Metabotropic Glutamate 2/3 Receptor Antagonist with Antidepressant-Like Activity.
J Med Chem
; 59(24): 10974-10993, 2016 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28002967
6.
Structure of a putative BenF-like porin from Pseudomonas fluorescens Pf-5 at 2.6 A resolution.
Proteins
; 78(14): 3056-62, 2010 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20737437
7.
Structures of the autoproteolytic domain from the Saccharomyces cerevisiae nuclear pore complex component, Nup145.
Proteins
; 78(8): 1992-8, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20310066
8.
Rapid-access, high-throughput synchrotron crystallography for drug discovery.
Trends Pharmacol Sci
; 33(5): 261-7, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22521107
9.
Structural underpinnings of nitrogen regulation by the prototypical nitrogen-responsive transcriptional factor NrpR.
Structure
; 18(11): 1512-21, 2010 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-21070950
10.
Structures of PHR domains from Mus musculus Phr1 (Mycbp2) explain the loss-of-function mutation (Gly1092-->Glu) of the C. elegans ortholog RPM-1.
J Mol Biol
; 397(4): 883-92, 2010 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-20156452
11.
Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant.
Protein Eng Des Sel
; 23(5): 375-84, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20150177
12.
SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo.
Mol Cancer Ther
; 8(12): 3181-90, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19934279