Detalhe da pesquisa
1.
First-in-human randomized study of RNAi therapeutic RG6346 for chronic hepatitis B virus infection.
J Hepatol
; 79(5): 1139-1149, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37524230
2.
Hepatitis B Surface Antigen Levels Can Be Used to Rule Out Cirrhosis in Hepatitis B e Antigen-Positive Chronic Hepatitis B: Results From the SONIC-B Study.
J Infect Dis
; 225(11): 1967-1973, 2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32318704
3.
Clinical Study of Single-Stranded Oligonucleotide RO7062931 in Healthy Volunteers and Patients With Chronic Hepatitis B.
Hepatology
; 74(4): 1795-1808, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34037271
4.
Composition of HBsAg is predictive of HBsAg loss during treatment in patients with HBeAg-positive chronic hepatitis B.
J Hepatol
; 74(2): 283-292, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32931877
5.
Liver safety assessment in clinical trials of new agents for chronic hepatitis B.
J Viral Hepat
; 27(2): 96-109, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31828894
6.
Quantitation of large, middle and small hepatitis B surface proteins in HBeAg-positive patients treated with peginterferon alfa-2a.
Liver Int
; 40(2): 324-332, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31721419
7.
Genetic variation in FCER1A predicts peginterferon alfa-2a-induced hepatitis B surface antigen clearance in East Asian patients with chronic hepatitis B.
J Viral Hepat
; 26(9): 1040-1049, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30972912
8.
Efficacy and Safety of Peginterferon Alfa-2a (40KD) in Children With Chronic Hepatitis B: The PEG-B-ACTIVE Study.
Hepatology
; 68(5): 1681-1694, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29689122
9.
Serum HBV RNA as a Predictor of Peginterferon Alfa-2a Response in Patients With HBeAg-Positive Chronic Hepatitis B.
J Infect Dis
; 218(7): 1066-1074, 2018 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29741634
11.
Use of an integrated modelling and simulation approach to develop a simplified peginterferon alfa-2a dosing regimen for children with hepatitis C.
Br J Clin Pharmacol
; 81(4): 658-66, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26529640
12.
Durability of Response in Children Treated With Pegylated Interferon alfa [corrected] 2a ± Ribavirin for Chronic Hepatitis C.
J Pediatr Gastroenterol Nutr
; 62(1): 93-6, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26284539
13.
Long-term growth outcomes in children treated for chronic hepatitis C.
J Pediatr
; 165(6): 1252-4, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25241178
14.
Predicting early and sustained virological responses in prior nonresponders to pegylated interferon alpha-2b plus ribavirin retreated with peginterferon alpha-2a plus ribavirin and the benefit-risk ratio of retreatment.
J Clin Gastroenterol
; 47(9): 786-93, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23442834
15.
A single ascending dose study of single-stranded oligodeoxyribonucleotide RO7062931 in Chinese healthy volunteers.
Clin Transl Sci
; 16(7): 1272-1282, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37147890
16.
Very low probability of significant liver inflammation in chronic hepatitis B patients with low ALT levels in the absence of liver fibrosis.
Aliment Pharmacol Ther
; 52(8): 1399-1406, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32886813
17.
Peginterferon alfa-2a (40 kD) stopping rules in chronic hepatitis B: a systematic review and meta-analysis of individual participant data.
Antivir Ther
; 24(2): 133-140, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30865588
18.
Optimisation of the use of APRI and FIB-4 to rule out cirrhosis in patients with chronic hepatitis B: results from the SONIC-B study.
Lancet Gastroenterol Hepatol
; 4(7): 538-544, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30975477
19.
Adherence to enfuvirtide and its impact on treatment efficacy.
AIDS Res Hum Retroviruses
; 24(2): 141-8, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18240965
20.
No association between IFNL3 (IL28B) genotype and response to peginterferon alfa-2a in HBeAg-positive or -negative chronic hepatitis B.
PLoS One
; 13(7): e0199198, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30016335