Detalhe da pesquisa
1.
Association of seasonal changes in circulating cortisol concentrations with the expression of cortisol biosynthetic enzymes and a glucocorticoid receptor in the blubber of common bottlenose dolphin.
Gen Comp Endocrinol
; 352: 114516, 2024 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38593942
2.
Design, synthesis, structure-activity relationship studies, and evaluation of novel GLS1 inhibitors.
Bioorg Med Chem Lett
; 87: 129266, 2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37011768
3.
Morphinan derivatives with an oxabicyclo[3.2.1]octane structure as dual agonists toward δ and κ opioid receptors.
Bioorg Med Chem
; 53: 116552, 2022 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34894610
4.
Essential structure of orexin 1 receptor antagonist YNT-707, part III: Role of the 14-hydroxy and the 3-methoxy groups in antagonistic activity toward the orexin 1 receptor in YNT-707 derivatives lacking the 4,5-epoxy ring.
Bioorg Med Chem
; 27(8): 1747-1758, 2019 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30871861
5.
In Silico Screening Identified Novel Small-molecule Antagonists of PAC1 Receptor.
J Pharmacol Exp Ther
; 365(1): 1-8, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29363578
6.
Essential structure of orexin 1 receptor antagonist YNT-707, Part II: Drastic effect of the 14-hydroxy group on the orexin 1 receptor antagonistic activity.
Bioorg Med Chem Lett
; 28(4): 774-777, 2018 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29338909
7.
Design, synthesis, and evaluation of novel inhibitors for wild-type human serine racemase.
Bioorg Med Chem Lett
; 28(3): 441-445, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29277459
8.
Essential structure of orexin 1 receptor antagonist YNT-707, Part I: Role of the 4,5-epoxy ring for binding with orexin 1 receptor.
Bioorg Med Chem Lett
; 27(17): 4176-4179, 2017 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28739044
9.
Triethylated chromones with substituted naphthalenes as tubulin inhibitors.
Bioorg Med Chem
; 24(22): 6048-6057, 2016 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27707623
10.
[Strengthening Cooperation between Medical and Nursing Care(Part 2) - A Collaborative Meeting of Home Care Doctors, Dentists, and Care Managers in Shinjuku City].
Gan To Kagaku Ryoho
; 43(Suppl 1): 11-13, 2016 Dec.
Artigo
em Japonês
| MEDLINE | ID: mdl-28028267
11.
[Strengthening Cooperation between Medical and Nursing Care - A Collaborative Meeting of Home Care Doctors and Care Managers in Shinjuku-City].
Gan To Kagaku Ryoho
; 42 Suppl 1: 3-4, 2015 Dec.
Artigo
em Japonês
| MEDLINE | ID: mdl-26809395
12.
Comprehensive expression analysis of hormone-like substances in the subcutaneous adipose tissue of the common bottlenose dolphin Tursiops truncatus.
Sci Rep
; 14(1): 12515, 2024 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38822022
13.
Design and synthesis of pyrido[2,3-d]pyrimidine derivatives for a novel PAC1 receptor antagonist.
Eur J Med Chem
; 231: 114160, 2022 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35124531
14.
Towards non-invasive heart rate monitoring in free-ranging cetaceans: a unipolar suction cup tag measured the heart rate of trained Risso's dolphins.
Philos Trans R Soc Lond B Biol Sci
; 376(1831): 20200225, 2021 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34176321
15.
A molecular interaction field describing nonconventional intermolecular interactions and its application to protein-ligand interaction prediction.
J Mol Graph Model
; 96: 107515, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31896525
16.
Fragment-based discovery of the first nonpeptidyl inhibitor of an S46 family peptidase.
Sci Rep
; 9(1): 13587, 2019 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31537874
17.
Investigation of substrate recognition for cytochrome P450 1A2 mediated by water molecules using docking and molecular dynamics simulations.
J Mol Graph Model
; 74: 326-336, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28475969
18.
A docking model of dapsone bound to HLA-B*13:01 explains the risk of dapsone hypersensitivity syndrome.
J Dermatol Sci
; 88(3): 320-329, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28870516
19.
Synthesis of Potent and Selective Inhibitors of Aldo-Keto Reductase 1B10 and Their Efficacy against Proliferation, Metastasis, and Cisplatin Resistance of Lung Cancer Cells.
J Med Chem
; 60(20): 8441-8455, 2017 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28976752
20.
Design and Synthesis of Potent and Highly Selective Orexin 1 Receptor Antagonists with a Morphinan Skeleton and Their Pharmacologies.
J Med Chem
; 60(3): 1018-1040, 2017 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28051300