Detalhe da pesquisa
1.
The discovery of a new structural class of cyclin-dependent kinase inhibitors, aminoimidazo[1,2-a]pyridines.
Mol Cancer Ther
; 3(1): 1-9, 2004 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-14749470
2.
Synthesis, structure-activity relationship, and biological studies of indolocarbazoles as potent cyclin D1-CDK4 inhibitors.
J Med Chem
; 46(11): 2027-30, 2003 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-12747775
3.
Kinetic characterization of novel pyrazole TGF-beta receptor I kinase inhibitors and their blockade of the epithelial-mesenchymal transition.
Biochemistry
; 44(7): 2293-304, 2005 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-15709742
4.
Structure-based design of a new class of highly selective aminoimidazo[1,2-a]pyridine-based inhibitors of cyclin dependent kinases.
Bioorg Med Chem Lett
; 15(7): 1943-7, 2005 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15780638
5.
Synthesis of quinolinyl/isoquinolinyl[a]pyrrolo [3,4-c] carbazoles as cyclin D1/CDK4 inhibitors.
Bioorg Med Chem Lett
; 13(7): 1231-5, 2003 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-12657252
6.
Preparation of novel aza-1,7-annulated indoles and their conversion to potent indolocarbazole kinase inhibitors.
Bioorg Med Chem Lett
; 14(15): 3925-8, 2004 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-15225699
7.
Aminoimidazo[1,2-a]pyridines as a new structural class of cyclin-dependent kinase inhibitors. Part 1: Design, synthesis, and biological evaluation.
Bioorg Med Chem Lett
; 14(24): 6095-9, 2004 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-15546737
8.
Synthesis of 1,7-annulated indoles and their applications in the studies of cyclin dependent kinase inhibitors.
Bioorg Med Chem Lett
; 14(12): 3057-61, 2004 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-15149644
9.
1,7-annulated indolocarbazoles as cyclin-dependent kinase inhibitors.
Bioorg Med Chem Lett
; 14(12): 3217-20, 2004 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-15149678
10.
Studies on cyclin-dependent kinase inhibitors: indolo-[2,3-a]pyrrolo[3,4-c]carbazoles versus bis-indolylmaleimides.
Bioorg Med Chem Lett
; 13(21): 3841-6, 2003 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-14552792
11.
Novel, potent and selective cyclin D1/CDK4 inhibitors: indolo[6,7-a]pyrrolo[3,4-c]carbazoles.
Bioorg Med Chem Lett
; 13(14): 2261-7, 2003 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-12824014
12.
Aryl[a]pyrrolo[3,4-c]carbazoles as selective cyclin D1-CDK4 inhibitors.
Bioorg Med Chem Lett
; 13(21): 3835-9, 2003 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-14552791