Detalhe da pesquisa
1.
The promise and peril of targeting cell metabolism for cancer therapy.
Cancer Immunol Immunother
; 69(2): 255-261, 2020 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-31781842
2.
Coexpression of NOS2 and COX2 accelerates tumor growth and reduces survival in estrogen receptor-negative breast cancer.
Proc Natl Acad Sci U S A
; 114(49): 13030-13035, 2017 12 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29087320
3.
The selective ROCK2 inhibitor KD025 reduces IL-17 secretion in human peripheral blood mononuclear cells independent of IL-1 and IL-6.
Eur J Immunol
; 48(10): 1679-1686, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30098001
4.
Cutting Edge: Selective Oral ROCK2 Inhibitor Reduces Clinical Scores in Patients with Psoriasis Vulgaris and Normalizes Skin Pathology via Concurrent Regulation of IL-17 and IL-10.
J Immunol
; 198(10): 3809-3814, 2017 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28389592
5.
Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism.
Blood
; 127(17): 2144-54, 2016 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26983850
6.
Selective oral ROCK2 inhibitor down-regulates IL-21 and IL-17 secretion in human T cells via STAT3-dependent mechanism.
Proc Natl Acad Sci U S A
; 111(47): 16814-9, 2014 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-25385601
7.
LTßR signalling preferentially accelerates oncogenic AKT-initiated liver tumours.
Gut
; 65(10): 1765-75, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26206664
8.
Tumor-induced CD11b(+) Gr-1(+) myeloid-derived suppressor cells exacerbate immune-mediated hepatitis in mice in a CD40-dependent manner.
Eur J Immunol
; 45(4): 1148-58, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25616156
9.
Killer immunoglobulin-like receptor (KIR) and KIR-ligand genotype do not correlate with clinical outcome of renal cell carcinoma patients receiving high-dose IL2.
Cancer Immunol Immunother
; 65(12): 1523-1532, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27695964
10.
Regulatory T cells and myeloid-derived suppressor cells in the tumor microenvironment undergo Fas-dependent cell death during IL-2/αCD40 therapy.
J Immunol
; 192(12): 5821-9, 2014 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24808361
11.
Serum-based tracking of de novo initiated liver cancer progression reveals early immunoregulation and response to therapy.
J Hepatol
; 63(5): 1181-9, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26143441
12.
Delineation of antigen-specific and antigen-nonspecific CD8(+) memory T-cell responses after cytokine-based cancer immunotherapy.
Blood
; 119(13): 3073-83, 2012 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-22251483
13.
IFN-gamma mediates CD4+ T-cell loss and impairs secondary antitumor responses after successful initial immunotherapy.
Nat Med
; 13(3): 354-60, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17334371
14.
Taking a BiTE out of Lymphoma: Bispecific Antibodies in B-Cell Non-Hodgkin Lymphoma.
Cancers (Basel)
; 16(9)2024 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38730677
15.
NOS2 enhances KRAS-induced lung carcinogenesis, inflammation and microRNA-21 expression.
Int J Cancer
; 132(1): 9-18, 2013 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22618808
16.
Macrophage migration inhibitory factor induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma.
Int J Cancer
; 132(4): 785-94, 2013 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22821831
17.
TCR-dependent and -independent activation underlie liver-specific regulation of NKT cells.
J Immunol
; 186(2): 838-47, 2011 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21148802
18.
Itaconic acid underpins hepatocyte lipid metabolism in non-alcoholic fatty liver disease in male mice.
Nat Metab
; 5(6): 981-995, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37308721
19.
Pyruvate dehydrogenase operates as an intramolecular nitroxyl generator during macrophage metabolic reprogramming.
Nat Commun
; 14(1): 5114, 2023 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37607904
20.
Successful immunotherapy with IL-2/anti-CD40 induces the chemokine-mediated mitigation of an immunosuppressive tumor microenvironment.
Proc Natl Acad Sci U S A
; 106(46): 19455-60, 2009 Nov 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-19892741