Detalhe da pesquisa
1.
Characterizing the Blood-Stage Antimalarial Activity of Tafenoquine in Healthy Volunteers Experimentally Infected With Plasmodium falciparum.
Clin Infect Dis
; 76(11): 1919-1927, 2023 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36795050
2.
R-praziquantel integrated population pharmacokinetics in preschool- and school-aged African children infected with Schistosoma mansoni and S. haematobium and Lao adults infected with Opisthorchis viverrini.
J Pharmacokinet Pharmacodyn
; 49(3): 293-310, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35024995
3.
Model-Informed Drug Development for Malaria Therapeutics.
Annu Rev Pharmacol Toxicol
; 58: 567-582, 2018 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28992431
4.
Model-informed drug repurposing: A pharmacometric approach to novel pathogen preparedness, response and retrospection.
Br J Clin Pharmacol
; 87(9): 3388-3397, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33534138
5.
Factors affecting the electrocardiographic QT interval in malaria: A systematic review and meta-analysis of individual patient data.
PLoS Med
; 17(3): e1003040, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32134952
6.
Correction to: R-praziquantel integrated population pharmacokinetics in preschool- and school-aged African children infected with Schistosoma mansoni and S. haematobium and Lao adults infected with Opisthorchis viverrini.
J Pharmacokinet Pharmacodyn
; 49(3): 395, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35119619
7.
Bioequivalence of oral and intravenous carbamazepine formulations in adult patients with epilepsy.
Epilepsia
; 56(6): 915-23, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25982590
8.
Vigabatrin pediatric dosing information for refractory complex partial seizures: results from a population dose-response analysis.
Epilepsia
; 55(12): e134-8, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25311090
9.
Liver-targeted polymeric prodrugs delivered subcutaneously improve tafenoquine therapeutic window for malaria radical cure.
Sci Adv
; 10(16): eadk4492, 2024 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38640243
10.
Gabapentin to pregabalin therapy transition: a pharmacokinetic simulation.
Am J Ther
; 20(1): 32-6, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23018586
11.
PBPK modeling of ivermectin-Considerations for the purpose of developing alternative routes to optimize its safety profile.
CPT Pharmacometrics Syst Pharmacol
; 12(5): 598-609, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36840414
12.
Development and application of a PBPK modeling strategy to support antimalarial drug development.
CPT Pharmacometrics Syst Pharmacol
; 12(9): 1335-1346, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37587640
13.
Pharmacokinetics and pharmacodynamics of artesunate and dihydroartemisinin following oral treatment in pregnant women with asymptomatic Plasmodium falciparum infections in Kinshasa DRC.
Malar J
; 10: 49, 2011 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21352601
14.
Population pharmacokinetics of artesunate and dihydroartemisinin in pregnant and non-pregnant women with malaria.
Malar J
; 10: 114, 2011 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21548983
15.
Registry initiated to characterize vision loss associated with vigabatrin therapy.
Epilepsy Behav
; 22(4): 710-7, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21978471
16.
Retrospective Analysis Using Pharmacokinetic/Pharmacodynamic Modeling and Simulation Offers Improvements in Efficiency of the Design of Volunteer Infection Studies for Antimalarial Drug Development.
Clin Transl Sci
; 14(2): 712-719, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33326705
17.
Model-Informed Drug Development for Anti-Infectives: State of the Art and Future.
Clin Pharmacol Ther
; 109(4): 867-891, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33555032
18.
Liver-targeted polymeric prodrugs of 8-aminoquinolines for malaria radical cure.
J Control Release
; 331: 213-227, 2021 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33378692
19.
Impact of Disease on Plasma and Lung Exposure of Chloroquine, Hydroxychloroquine and Azithromycin: Application of PBPK Modeling.
Clin Pharmacol Ther
; 108(5): 976-984, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32531808
20.
Pharmacokinetics and Pharmacological Properties of Chloroquine and Hydroxychloroquine in the Context of COVID-19 Infection.
Clin Pharmacol Ther
; 108(6): 1135-1149, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32687630