Detalhe da pesquisa
1.
Development of an ICOSL and BAFF bispecific inhibitor AMG 570 for systemic lupus erythematosus treatment.
Clin Exp Rheumatol
; 37(6): 906-914, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30789152
2.
Spontaneous colitis occurrence in transgenic mice with altered B7-mediated costimulation.
J Immunol
; 181(8): 5278-88, 2008 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18832683
3.
G-protein-coupled receptor 35 is a target of the asthma drugs cromolyn disodium and nedocromil sodium.
Pharmacology
; 86(1): 1-5, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20559017
4.
Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide Are Potent TMEM16A Antagonists That Fully Bronchodilate Airways.
Front Pharmacol
; 10: 51, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30837866
5.
Discovery, Optimization, and in Vivo Evaluation of Benzimidazole Derivatives AM-8508 and AM-9635 as Potent and Selective PI3Kδ Inhibitors.
J Med Chem
; 59(1): 431-47, 2016 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26652588
6.
Discovery and in Vivo Evaluation of the Potent and Selective PI3Kδ Inhibitors 2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-6-fluoro-N-methyl-3-(2-pyridinyl)-4-quinolinecarboxamide (AM-0687) and 2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-5-fluoro-N-methyl-3-(2-pyridinyl)-4-quinolinecarboxamide (AM-1430).
J Med Chem
; 59(15): 7252-67, 2016 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27411843
7.
Discovery and in vivo evaluation of (S)-N-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine (AMG319) and related PI3Kδ inhibitors for inflammation and autoimmune disease.
J Med Chem
; 58(1): 480-511, 2015 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25469863
8.
Potent activity of soluble B7RP-1-Fc in therapy of murine tumors in syngeneic hosts.
Int J Cancer
; 103(4): 501-7, 2003 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-12478666