Detalhe da pesquisa
1.
Targeted inhibition of eIF4A suppresses B-cell receptor-induced translation and expression of MYC and MCL1 in chronic lymphocytic leukemia cells.
Cell Mol Life Sci
; 78(17-18): 6337-6349, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34398253
2.
B-cell receptor signaling induces proteasomal degradation of PDCD4 via MEK1/2 and mTORC1 in malignant B cells.
Cell Signal
; 94: 110311, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35306137
3.
Target-Based Screening against eIF4A1 Reveals the Marine Natural Product Elatol as a Novel Inhibitor of Translation Initiation with In Vivo Antitumor Activity.
Clin Cancer Res
; 24(17): 4256-4270, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29844128
4.
The Dual Syk/JAK Inhibitor Cerdulatinib Antagonizes B-cell Receptor and Microenvironmental Signaling in Chronic Lymphocytic Leukemia.
Clin Cancer Res
; 23(9): 2313-2324, 2017 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27697994
5.
PEITC-mediated inhibition of mRNA translation is associated with both inhibition of mTORC1 and increased eIF2α phosphorylation in established cell lines and primary human leukemia cells.
Oncotarget
; 7(46): 74807-74819, 2016 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27579538