Detalhe da pesquisa
1.
Infiltration of inflammatory macrophages and neutrophils and widespread pyroptosis in lung drive influenza lethality in nonhuman primates.
PLoS Pathog
; 18(3): e1010395, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35271686
2.
Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection.
PLoS Pathog
; 17(6): e1009674, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34181694
3.
Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals.
PLoS Pathog
; 15(10): e1008074, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31609991
4.
Peripheral Blood Biomarkers of Disease Outcome in a Monkey Model of Rift Valley Fever Encephalitis.
J Virol
; 92(3)2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29118127
5.
Widespread Virus Replication in Alveoli Drives Acute Respiratory Distress Syndrome in Aerosolized H5N1 Influenza Infection of Macaques.
J Immunol
; 198(4): 1616-1626, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28062701
6.
Persistent accumulation of gut macrophages with impaired phagocytic function correlates with SIV disease progression in macaques.
Eur J Immunol
; 47(11): 1925-1935, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28667761
7.
Macrophage accumulation in gut mucosa differentiates AIDS from chronic SIV infection in rhesus macaques.
Eur J Immunol
; 46(2): 446-54, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26549608
8.
Macrophages and Myeloid Dendritic Cells Lose T Cell-Stimulating Function in Simian Immunodeficiency Virus Infection Associated with Diminished IL-12 and IFN-α Production.
J Immunol
; 195(7): 3284-92, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26297760
9.
Blocking TLR7- and TLR9-mediated IFN-α production by plasmacytoid dendritic cells does not diminish immune activation in early SIV infection.
PLoS Pathog
; 9(7): e1003530, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23935491
10.
Virus-encoded TLR ligands reveal divergent functional responses of mononuclear phagocytes in pathogenic simian immunodeficiency virus infection.
J Immunol
; 190(5): 2188-98, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23338235
11.
Predictors of HIV rebound differ by timing of antiretroviral therapy initiation.
JCI Insight
; 9(3)2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38329130
12.
SIV infection of rhesus macaques differentially impacts mononuclear phagocyte responses to virus-derived TLR agonists.
J Med Primatol
; 42(5): 247-53, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23905748
13.
Application of ultrasensitive digital ELISA for p24 enables improved evaluation of HIV-1 reservoir diversity and growth kinetics in viral outgrowth assays.
Sci Rep
; 13(1): 10958, 2023 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37414788
14.
ADP ribosylation factor 1 activity is required to recruit AP-1 to the major histocompatibility complex class I (MHC-I) cytoplasmic tail and disrupt MHC-I trafficking in HIV-1-infected primary T cells.
J Virol
; 85(23): 12216-26, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21917951
15.
Ex Vivo Differentiation of Resting CD4+ T Lymphocytes Enhances Detection of Replication Competent HIV-1 in Viral Outgrowth Assays.
Methods Mol Biol
; 2407: 315-331, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-34985673
16.
Inhibitors of HIV-1 Nef-Mediated Activation of the Myeloid Src-Family Kinase Hck Block HIV-1 Replication in Macrophages and Disrupt MHC-I Downregulation.
ACS Infect Dis
; 8(1): 91-105, 2022 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34985256
17.
Novel Compound Inhibitors of HIV-1NL4-3 Vpu.
Viruses
; 14(4)2022 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35458546
18.
The 2000HIV study: Design, multi-omics methods and participant characteristics.
Front Immunol
; 13: 982746, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36605197
19.
A highly multiplexed droplet digital PCR assay to measure the intact HIV-1 proviral reservoir.
Cell Rep Med
; 2(4): 100243, 2021 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33948574
20.
Single center, open label dose escalating trial evaluating once weekly oral ixazomib in ART-suppressed, HIV positive adults and effects on HIV reservoir size in vivo.
EClinicalMedicine
; 42: 101225, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34901797