Detalhe da pesquisa
1.
The CRTC1-SIK1 pathway regulates entrainment of the circadian clock.
Cell
; 154(5): 1100-1111, 2013 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-23993098
2.
A transcriptomics-based drug repositioning approach to identify drugs with similar activities for the treatment of muscle pathologies in spinal muscular atrophy (SMA) models.
Hum Mol Genet
; 33(5): 400-425, 2024 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37947217
3.
Investigating Eukaryotic Elongation Factor 2 Kinase/Eukaryotic Translation Elongation Factor 2 Pathway Regulation and Its Role in Protein Synthesis Impairment during Disuse-Induced Skeletal Muscle Atrophy.
Am J Pathol
; 193(6): 813-828, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36871751
4.
Control of backbone chemistry and chirality boost oligonucleotide splice switching activity.
Nucleic Acids Res
; 50(10): 5443-5466, 2022 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35061895
5.
A Purposefully Designed pH/GSH-Responsive MnFe-Based Metal-Organic Frameworks as Cascade Nanoreactor for Enhanced Chemo-Chemodynamic-Starvation Synergistic Therapy.
Small
; 19(50): e2303403, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37649230
6.
Application of Antisense Conjugates for the Treatment of Myotonic Dystrophy Type 1.
Int J Mol Sci
; 24(3)2023 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36769018
7.
AR cooperates with SMAD4 to maintain skeletal muscle homeostasis.
Acta Neuropathol
; 143(6): 713-731, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35522298
8.
Mutation-independent Proteomic Signatures of Pathological Progression in Murine Models of Duchenne Muscular Dystrophy.
Mol Cell Proteomics
; 19(12): 2047-2068, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32994316
9.
Doublecortin-like Kinase 1 Regulates α-Synuclein Levels and Toxicity.
J Neurosci
; 40(2): 459-477, 2020 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31748376
10.
Molecular correction of Duchenne muscular dystrophy by splice modulation and gene editing.
RNA Biol
; 18(7): 1048-1062, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33472516
11.
Application of CRISPR-Cas9-Mediated Genome Editing for the Treatment of Myotonic Dystrophy Type 1.
Mol Ther
; 28(12): 2527-2539, 2020 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33171139
12.
Light modulation ameliorates expression of circadian genes and disease progression in spinal muscular atrophy mice.
Hum Mol Genet
; 27(20): 3582-3597, 2018 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29982483
13.
Africa - first institute for neuroscience.
Nature
; 574(7778): 333, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31616095
14.
Muscle overexpression of Klf15 via an AAV8-Spc5-12 construct does not provide benefits in spinal muscular atrophy mice.
Gene Ther
; 27(10-11): 505-515, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32313099
15.
Spinal muscular atrophy: antisense oligonucleotide therapy opens the door to an integrated therapeutic landscape.
Hum Mol Genet
; 26(R2): R151-R159, 2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28977438
16.
Alpha-synuclein induces the unfolded protein response in Parkinson's disease SNCA triplication iPSC-derived neurons.
Hum Mol Genet
; 26(22): 4441-4450, 2017 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28973645
17.
Extracellular microRNAs exhibit sequence-dependent stability and cellular release kinetics.
RNA Biol
; 16(5): 696-706, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30836828
18.
Knockdown and replacement therapy mediated by artificial mirtrons in spinocerebellar ataxia 7.
Nucleic Acids Res
; 45(13): 7870-7885, 2017 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28575281
19.
Systemic peptide-mediated oligonucleotide therapy improves long-term survival in spinal muscular atrophy.
Proc Natl Acad Sci U S A
; 113(39): 10962-7, 2016 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27621445
20.
Selective release of muscle-specific, extracellular microRNAs during myogenic differentiation.
Hum Mol Genet
; 25(18): 3960-3974, 2016 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27466195