Detalhe da pesquisa
1.
Ugi 5-center-4-component reaction of α-amino aldehydes and its application in synthesis of 2-oxopiperazines.
Mol Divers
; 28(1): 229-248, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38104301
2.
Synthesis and biological evaluation of novel 3-(5-substituted-1H-indol-3-yl)pyrrolidine-2,5-dione derivatives with a dual affinity for serotonin 5-HT1A receptor and SERT.
Bioorg Chem
; 141: 106903, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37827015
3.
Novel multi-target ligands of dopamine and serotonin receptors for the treatment of schizophrenia based on indazole and piperazine scaffolds-synthesis, biological activity, and structural evaluation.
J Enzyme Inhib Med Chem
; 38(1): 2209828, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37184096
4.
Synthesis of new 4-butyl-arylpiperazine-3-(1H-indol-3-yl)pyrrolidine-2,5-dione derivatives and evaluation for their 5-HT1A and D2 receptor affinity and serotonin transporter inhibition.
Bioorg Chem
; 97: 103662, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32086055
5.
Synthesis and biological investigations of 3ß-aminotropane arylamide derivatives with atypical antipsychotic profile.
Med Chem Res
; 27(8): 1906-1928, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30100693
6.
Model structure-activity relationship studies of potential tropane 5HT1A, 5HT2A, and D2 receptor ligands.
Med Chem Res
; 22(7): 3148-3153, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23710122
7.
Discovery of novel arylpiperazine-based DA/5-HT modulators as potential antipsychotic agents - Design, synthesis, structural studies and pharmacological profiling.
Eur J Med Chem
; 252: 115285, 2023 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37027998
8.
Synthesis and biological evaluation of new multi-target 3-(1H-indol-3-yl)pyrrolidine-2,5-dione derivatives with potential antidepressant effect.
Eur J Med Chem
; 183: 111736, 2019 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31586817
9.
Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT1A activity. Part 4.
Eur J Med Chem
; 90: 21-32, 2015 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25461308
10.
Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT(1A) activity. Part 5.
Eur J Med Chem
; 98: 221-36, 2015 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26043160
11.
Synthesis and biological evaluation of novel pyrrolidine-2,5-dione derivatives as potential antidepressant agents. Part 1.
Eur J Med Chem
; 63: 484-500, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23524160