Alcohol Text Messages: A Developmental Study.

Risky paternal alcohol use is associated with maternal alcohol use during pregnancy, poor fetal and infant outcomes, domestic violence and depression. This study developed 30 SMS text messages about alcohol for fathers who drink at risky levels. The text messages were developed using two motivational styles: messages presented in a second person voice and the same messages presented in a child's voice. Fifty-one fathers were recruited through social media to complete an online survey rating the SMS text messages for message importance and likelihood of seeking further information and measuring risky alcohol use and psychosocial distress. Seventeen participants then participated in a semi-structured qualitative interview. Fathers rated the text messages presented in the child's voice as more important than messages presented in the second person. Qualitative data supported survey results that motivational SMS text messages could provide an acceptable way to raise awareness of risky alcohol consumption for future fathers.

Plasma cholinesterase changes during pregnancy. Their interpretation as a cause of suxamethonium-induced apnoea.

Cholinesterase activities were measured on serum from 941 pregnant women distributed evenly throughout the 40 weeks of gestation. A rapid fall has been shown to occur during the first trimester to a level which did not alter significantly during the remainder of pregnancy. Even lower values were observed in 105 patients examined during the first 7 days following delivery. Enzyme activity was used to determine the probable incidence of a prolonged reaction to suxamethonium in obstetric patients. The risk was greatest in the immediate post partum period affecting 11% of the patients investigated.

Is serum cholinesterase activity a predictor of succinyl choline sensitivity? An assessment of four methods.

Four methods for measuring serum cholinesterase activity have been applied to sera of normal individuals and of patients shown to be sensitive to short-acting muscle relaxants of the succinyldicholine type. They have been assessed according to their ability to differentiate between sensitive and insensitive individuals on the basis of enzyme activity measurements alone. The method described, based upon that of Dietz et al. [Clin. Chem. 19, 1309 (1973)], in which propionylthiocholine is used as substrate, is best for this purpose, being capable of identifying over 90% of affected individuals with no false positives. Acetylcholine and butyrylthiocholine are slightly inferior substrates in this respect, and benzoylcholine gives little useful information.