Detalhe da pesquisa
1.
A framework enabling LLMs into regulatory environment for transparency and trustworthiness and its application to drug labeling document.
Regul Toxicol Pharmacol
; 149: 105613, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38570021
2.
Classifying Free Texts Into Predefined Sections Using AI in Regulatory Documents: A Case Study with Drug Labeling Documents.
Chem Res Toxicol
; 36(8): 1290-1299, 2023 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37487037
3.
A Weakly Supervised Deep Learning Framework for Whole Slide Classification to Facilitate Digital Pathology in Animal Study.
Chem Res Toxicol
; 36(8): 1321-1331, 2023 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37540590
4.
Development of benchmark datasets for text mining and sentiment analysis to accelerate regulatory literature review.
Regul Toxicol Pharmacol
; 137: 105287, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36372266
5.
Systematic Identification of Molecular Targets and Pathways Related to Human Organ Level Toxicity.
Chem Res Toxicol
; 34(2): 412-421, 2021 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33251791
6.
Trade-off Predictivity and Explainability for Machine-Learning Powered Predictive Toxicology: An in-Depth Investigation with Tox21 Data Sets.
Chem Res Toxicol
; 34(2): 541-549, 2021 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33513003
7.
Transcriptome analysis reveals lung-specific miRNAs associated with impaired mucociliary clearance induced by cigarette smoke in an in vitro human airway tissue model.
Arch Toxicol
; 95(5): 1763-1778, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33704509
8.
Coordinated Regulation of UGT2B15 Expression by Long Noncoding RNA LINC00574 and hsa-miR-129-5p in HepaRG Cells.
Drug Metab Dispos
; 48(4): 297-306, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32086297
9.
Long noncoding RNA LINC00844-mediated molecular network regulates expression of drug metabolizing enzymes and nuclear receptors in human liver cells.
Arch Toxicol
; 94(5): 1637-1653, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32222775
10.
DLI-IT: a deep learning approach to drug label identification through image and text embedding.
BMC Med Inform Decis Mak
; 20(1): 68, 2020 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32293428
11.
Study of serious adverse drug reactions using FDA-approved drug labeling and MedDRA.
BMC Bioinformatics
; 20(Suppl 2): 97, 2019 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30871458
12.
HetEnc: a deep learning predictive model for multi-type biological dataset.
BMC Genomics
; 20(1): 638, 2019 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31395005
13.
Novel reference genes in colorectal cancer identify a distinct subset of high stage tumors and their associated histologically normal colonic tissues.
BMC Med Genet
; 20(1): 138, 2019 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31409279
14.
Technical advance in targeted NGS analysis enables identification of lung cancer risk-associated low frequency TP53, PIK3CA, and BRAF mutations in airway epithelial cells.
BMC Cancer
; 19(1): 1081, 2019 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31711466
15.
Multiple microRNAs function as self-protective modules in acetaminophen-induced hepatotoxicity in humans.
Arch Toxicol
; 92(2): 845-858, 2018 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-29067470
16.
Integrating Drug's Mode of Action into Quantitative Structure-Activity Relationships for Improved Prediction of Drug-Induced Liver Injury.
J Chem Inf Model
; 57(4): 1000-1006, 2017 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28350954
17.
LTMap: a web server for assessing the potential liver toxicity by genome-wide transcriptional expression data.
J Appl Toxicol
; 34(7): 805-9, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24022982
18.
PERform: assessing model performance with predictivity and explainability readiness formula.
J Environ Sci Health C Toxicol Carcinog
; : 1-16, 2024 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38619534
19.
Measurement and Mitigation of Bias in Artificial Intelligence: A Narrative Literature Review for Regulatory Science.
Clin Pharmacol Ther
; 115(4): 687-697, 2024 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38018360
20.
Text summarization with ChatGPT for drug labeling documents.
Drug Discov Today
; 29(6): 104018, 2024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38723763