Detalhe da pesquisa
1.
REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps.
Mol Cell
; 81(19): 4008-4025.e7, 2021 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34508659
2.
The BRCT Domains of the BRCA1 and BARD1 Tumor Suppressors Differentially Regulate Homology-Directed Repair and Stalled Fork Protection.
Mol Cell
; 72(1): 127-139.e8, 2018 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30244837
3.
DNA damage-induced phosphorylation of CtIP at a conserved ATM/ATR site T855 promotes lymphomagenesis in mice.
Proc Natl Acad Sci U S A
; 118(38)2021 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34521752
4.
CtIP-mediated DNA resection is dispensable for IgH class switch recombination by alternative end-joining.
Proc Natl Acad Sci U S A
; 117(41): 25700-25711, 2020 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32989150
5.
Activation of DSB processing requires phosphorylation of CtIP by ATR.
Mol Cell
; 49(4): 657-67, 2013 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23273981
6.
ATM/ATR Phosphorylation of CtIP on Its Conserved Sae2-like Domain Is Required for Genotoxin-Induced DNA Resection but Dispensable for Animal Development.
Cells
; 12(23)2023 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38067190
7.
CtIP is essential for early B cell proliferation and development in mice.
J Exp Med
; 216(7): 1648-1663, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31097467
8.
The UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic function.
Mol Cell Biol
; 30(11): 2787-98, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20351172
9.
BRCA1/BARD1 inhibition of mRNA 3' processing involves targeted degradation of RNA polymerase II.
Genes Dev
; 19(10): 1227-37, 2005 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15905410
10.
The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin.
J Biol Chem
; 278(37): 34743-6, 2003 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-12890688
11.
Mono- versus polyubiquitination: differential control of p53 fate by Mdm2.
Science
; 302(5652): 1972-5, 2003 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-14671306