Detalhe da pesquisa
1.
Crystallographic and Computational Insights into Isoform-Selective Dynamics in Nitric Oxide Synthase.
Biochemistry
; 63(6): 788-796, 2024 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38417024
2.
BCL6 BTB-specific inhibitor reversely represses T-cell activation, Tfh cells differentiation, and germinal center reaction in vivo.
Eur J Immunol
; 51(10): 2441-2451, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34287839
3.
Improving the solubility and antileukemia activity of Wnt/ß-catenin signaling inhibitors by disrupting molecular planarity.
Bioorg Med Chem
; 69: 116890, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35777269
4.
Regioselective alkylation of 2,4-dihydroxybenzyaldehydes and 2,4-dihydroxyacetophenones.
Tetrahedron Lett
; 952022 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35495552
5.
Repurposing Acitretin as an Antipseudomonal Agent Targeting the Pseudomonas aeruginosa Iron-Regulated Heme Oxygenase.
Biochemistry
; 60(9): 689-698, 2021 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33621054
6.
GTP-binding inhibitors increase LRRK2-linked ubiquitination and Lewy body-like inclusions.
J Cell Physiol
; 235(10): 7309-7320, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32180220
7.
BCL6 Inhibitor-Mediated Downregulation of Phosphorylated SAMHD1 and T Cell Activation Are Associated with Decreased HIV Infection and Reactivation.
J Virol
; 93(2)2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30355686
8.
BCL6 BTB-specific inhibition via FX1 treatment reduces Tfh cells and reverses lymphoid follicle hyperplasia in Indian rhesus macaque (Macaca mulatta).
J Med Primatol
; 49(1): 26-33, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31571234
9.
The effects of novel heme oxygenase inhibitors on the growth of Pseudomonas aeruginosa.
Microb Pathog
; 129: 64-67, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-30716393
10.
Correction to: The Asp99-Arg188 salt bridge of the Pseudomonas aeruginosa HemO is critical in allowing conformational flexibility during catalysis.
J Biol Inorg Chem
; 23(7): 1071, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30302600
11.
The Asp99-Arg188 salt bridge of the Pseudomonas aeruginosa HemO is critical in allowing conformational flexibility during catalysis.
J Biol Inorg Chem
; 23(7): 1057-1070, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30194537
12.
Attenuated Accumulation of Novel Fluorine (19F)-Labeled Bile Acid Analogues in Gallbladders of Fibroblast Growth Factor-15 (FGF15)-Deficient Mice.
Mol Pharm
; 15(11): 4827-4834, 2018 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30247920
13.
Incorporation of a Biguanide Scaffold Enhances Drug Uptake by Organic Cation Transporters 1 and 2.
Mol Pharm
; 14(8): 2726-2739, 2017 08 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28699756
14.
Iodobenzene-Catalyzed Synthesis of Phenanthridinones via Oxidative C-H Amidation.
J Org Chem
; 82(7): 3589-3596, 2017 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28245353
15.
One-pot sequential reaction to 2-substituted-phenanthridinones from N-methoxybenzamides.
Org Biomol Chem
; 15(20): 4390-4398, 2017 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28475192
16.
Novel LRRK2 GTP-binding inhibitors reduced degeneration in Parkinson's disease cell and mouse models.
Hum Mol Genet
; 23(23): 6212-22, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24993787
17.
Aminoquinoline-assisted vinylic C-H arylation of unsubstituted acrylamide for the selective synthesis of Z olefins.
Org Biomol Chem
; 14(12): 3298-306, 2016 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26932744
18.
Inhibitor Bound Crystal Structures of Bacterial Nitric Oxide Synthase.
Biochemistry
; 54(26): 4075-82, 2015 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26062720
19.
Cyclopropyl-containing positive allosteric modulators of metabotropic glutamate receptor subtype 5.
Bioorg Med Chem Lett
; 25(11): 2275-9, 2015 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25937015
20.
Cu-mediated direct regioselective C-2 chlorination of indoles.
Org Biomol Chem
; 13(34): 9000-4, 2015 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26247622