Detalhe da pesquisa
1.
Discovery and SAR of aryl hydroxy pyrimidinones as potent small molecule agonists of the GPCR APJ.
Bioorg Med Chem Lett
; 30(7): 126955, 2020 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32035698
2.
Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains.
PLoS Genet
; 11(12): e1005711, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26694027
3.
Correction: Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains.
PLoS Genet
; 12(3): e1005913, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26934746
4.
In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure.
Circ Heart Fail
; 14(3): e007351, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33663236
5.
Biphenyl Acid Derivatives as APJ Receptor Agonists.
J Med Chem
; 62(22): 10456-10465, 2019 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31724863
6.
(D)-2-tert-Butoxycarbonylamino-5,5-difluoro-5-phenyl-pentanoic acid: synthesis and incorporation into the growth hormone secretagogues.
Bioorg Med Chem Lett
; 18(14): 4072-4, 2008 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18554903
7.
Optimization of 1H-tetrazole-1-alkanenitriles as potent orally bioavailable growth hormone secretagogues.
Bioorg Med Chem Lett
; 18(6): 2067-72, 2008 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18282707
8.
Tetrazole based amides as growth hormone secretagogues.
Bioorg Med Chem Lett
; 18(8): 2536-9, 2008 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18378446
9.
Design and synthesis of tetrazole-based growth hormone secretagogue: the SAR studies of the O-benzyl serine side chain.
Bioorg Med Chem Lett
; 18(6): 1825-9, 2008 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18295486
10.
Discovery of a tetrazole-based growth hormone secretagogue: 4-(hydroxybutyl)carbamic acid 2-{5-[1-(2-amino-2-methylpropionylamino)-2- benzyloxyethyl]tetrazol-1-yl}ethyl ester (BMS-317180).
J Med Chem
; 50(24): 5890-3, 2007 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-17973363
11.
Discovery of a potent and novel motilin agonist.
J Med Chem
; 47(7): 1704-8, 2004 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-15027861
12.
P2Y6 receptor potentiates pro-inflammatory responses in macrophages and exhibits differential roles in atherosclerotic lesion development.
PLoS One
; 9(10): e111385, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25360548
13.
11ß-hydroxysteroid dehydrogenase type 1 gene knockout attenuates atherosclerosis and in vivo foam cell formation in hyperlipidemic apoEâ»/â» mice.
PLoS One
; 8(2): e53192, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23383297