Detalhe da pesquisa
1.
The epichaperome is an integrated chaperome network that facilitates tumour survival.
Nature
; 538(7625): 397-401, 2016 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27706135
2.
Chaperome Networks - Redundancy and Implications for Cancer Treatment.
Adv Exp Med Biol
; 1243: 87-99, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32297213
3.
Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2.
Nat Chem Biol
; 9(11): 677-84, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23995768
4.
Improving PD-1 blockade plus chemotherapy for complete remission of lung cancer by nanoPDLIM2.
bioRxiv
; 2024 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37546791
5.
Phosphorylation-Driven Epichaperome Assembly: A Critical Regulator of Cellular Adaptability and Proliferation.
Res Sq
; 2024 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38645031
6.
The tumor suppressor gene WWOX links the canonical and noncanonical NF-κB pathways in HTLV-I Tax-mediated tumorigenesis.
Blood
; 117(5): 1652-61, 2011 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-21115974
7.
How aberrant N-glycosylation can alter protein functionality and ligand binding: An atomistic view.
Structure
; 31(8): 987-1004.e8, 2023 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37343552
8.
Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation.
Nat Commun
; 14(1): 3742, 2023 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37353488
9.
Disease-specific interactome alterations via epichaperomics: the case for Alzheimer's disease.
FEBS J
; 289(8): 2047-2066, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34028172
10.
Epigenetic repression of PDZ-LIM domain-containing protein 2: implications for the biology and treatment of breast cancer.
J Biol Chem
; 285(16): 11786-92, 2010 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-20185823
11.
PDLIM2 suppresses human T-cell leukemia virus type I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradation.
Blood
; 113(18): 4370-80, 2009 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-19131544
12.
Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system.
Nat Commun
; 12(1): 4669, 2021 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34344873
13.
Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer.
Commun Biol
; 4(1): 1333, 2021 11 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34824367
14.
A Chemical Biology Approach to the Chaperome in Cancer-HSP90 and Beyond.
Cold Spring Harb Perspect Biol
; 12(4)2020 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30936118
15.
Bisubstrate-Type Chemical Probes Identify GRP94 as a Potential Target of Cytosine-Containing Adenosine Analogs.
ACS Chem Biol
; 15(4): 952-961, 2020 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32191434
16.
Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone.
Cell Rep
; 31(13): 107840, 2020 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32610141
17.
The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction.
Nat Commun
; 11(1): 319, 2020 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31949159
18.
Mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys polymorphism contributes to the variation in efficacy of sublingual nitroglycerin.
J Clin Invest
; 116(2): 506-11, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16440063
19.
Causative role of PDLIM2 epigenetic repression in lung cancer and therapeutic resistance.
Nat Commun
; 10(1): 5324, 2019 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31757943
20.
Paradigms for Precision Medicine in Epichaperome Cancer Therapy.
Cancer Cell
; 36(5): 559-573.e7, 2019 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31668946