Detalhe da pesquisa
1.
Phase I study of daily and weekly regimens of the orally administered MDM2 antagonist idasanutlin in patients with advanced tumors.
Invest New Drugs
; 39(6): 1587-1597, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34180037
2.
Current Evidence and Future Directions of Tranexamic Acid Use, Efficacy, and Dosing for Major Surgical Procedures.
J Cardiothorac Vasc Anesth
; 34(3): 782-790, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-31455576
3.
Noteworthy idiosyncrasies of 1α,25-dihydroxyvitamin D3 kinetics for extrapolation from mouse to man: Commentary.
Biopharm Drug Dispos
; 41(3): 126-148, 2020 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-32319119
4.
Highlighting Vitamin D Receptor-Targeted Activities of 1α,25-Dihydroxyvitamin D3 in Mice via Physiologically Based Pharmacokinetic-Pharmacodynamic Modeling.
Drug Metab Dispos
; 46(1): 75-87, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29084783
5.
Tranexamic Acid Dosing for Cardiac Surgical Patients With Chronic Renal Dysfunction: A New Dosing Regimen.
Anesth Analg
; 127(6): 1323-1332, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29309319
6.
Unequivocal evidence supporting the segregated flow intestinal model that discriminates intestine versus liver first-pass removal with PBPK modeling.
Biopharm Drug Dispos
; 38(3): 231-250, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-27977852
7.
Comparing early liver graft function from heart beating and living-donors: A pilot study aiming to identify new biomarkers of liver injury.
Biopharm Drug Dispos
; 38(5): 326-339, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28102538
8.
Metabolite Kinetics: The Segregated Flow Model for Intestinal and Whole Body Physiologically Based Pharmacokinetic Modeling to Describe Intestinal and Hepatic Glucuronidation of Morphine in Rats In Vivo.
Drug Metab Dispos
; 44(7): 1123-38, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27098743
9.
Physiologically-Based Pharmacokinetic-Pharmacodynamic Modeling of 1α,25-Dihydroxyvitamin D3 in Mice.
Drug Metab Dispos
; 44(2): 189-208, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26586377
10.
PBPK modeling to unravel nonlinear pharmacokinetics of verapamil to estimate the fractional clearance for verapamil N-demethylation in the recirculating rat liver preparation.
Drug Metab Dispos
; 43(4): 631-45, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25650380
11.
Pharmacokinetic modeling of tranexamic acid for patients undergoing cardiac surgery with normal renal function and model simulations for patients with renal impairment.
Biopharm Drug Dispos
; 36(5): 294-307, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25704361
12.
To the Editor.
Anesth Analg
; 128(6): e125-e126, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31094820
13.
Response to letter to the editor on "fractional clearance for verapamil N-demethylation in the isolated rat liver preparation".
Drug Metab Dispos
; 43(7): 1058-9, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25964425