Detalhe da pesquisa
1.
Computational Design and Crystal Structure of a Highly Efficient Benzoylecgonine Hydrolase.
Angew Chem Int Ed Engl
; 60(40): 21959-21965, 2021 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34351032
2.
The catalytic mechanism of S-acyltransferases: acylation is triggered on by a loose transition state and deacylation is turned off by a tight transition state.
Phys Chem Chem Phys
; 21(23): 12163-12172, 2019 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31144705
3.
Catalytic Reaction Mechanism for Drug Metabolism in Human Carboxylesterase-1: Cocaine Hydrolysis Pathway.
Mol Pharm
; 15(9): 3871-3880, 2018 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30095924
4.
Circular exponential amplification of photoinduced electron transfer using hairpin probes, G-quadruplex DNAzyme and silver nanocluster-labeled DNA for ultrasensitive fluorometric determination of pathogenic bacteria.
Mikrochim Acta
; 185(3): 168, 2018 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29594727
5.
Understanding the Catalytic Mechanism and the Nature of the Transition State of an Attractive Drug-Target Enzyme (Shikimate Kinase) by Quantum Mechanical/Molecular Mechanical (QM/MM) Studies.
Chemistry
; 23(64): 16380-16387, 2017 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28925075
6.
Understanding the Catalytic Mechanism and the Substrate Specificity of an Engineered Gluten Hydrolase by QM/MM Molecular Dynamics and Free Energy Simulations.
J Chem Inf Model
; 57(5): 1179-1186, 2017 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28462999
7.
Substrate-Assisted Catalysis in the Reaction Catalyzed by Salicylic Acid Binding Protein 2 (SABP2), a Potential Mechanism of Substrate Discrimination for Some Promiscuous Enzymes.
Biochemistry
; 54(34): 5366-75, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26244568
8.
Attack Site Density of a Highly-efficient PET Hydrolases.
Protein Pept Lett
; 30(6): 506-512, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37165591
9.
Understanding product specificity of protein lysine methyltransferases from QM/MM molecular dynamics and free energy simulations: the effects of mutation on SET7/9 beyond the Tyr/Phe switch.
J Chem Inf Model
; 52(2): 449-56, 2012 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22242964
10.
Ellman's method-based determination of acibenzolar-S-methyl in tobacco by transesterification with methanol and SABP2-catalyzed hydrolysis.
Anal Sci
; 38(5): 749-757, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35298794
11.
Stability and sugar recognition ability of ricin-like carbohydrate binding domains.
Biochemistry
; 50(19): 4097-104, 2011 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-21510689
12.
One- and Two-Proton Transfer Mechanisms Coexist in One Active Site.
J Phys Chem B
; 124(31): 6699-6708, 2020 08 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32663399
13.
Human Acetyl-CoA Carboxylase 1 Is an Isomerase: Carboxyl Transfer Is Activated by Catalytic Effect of Isomerization.
J Phys Chem B
; 123(31): 6757-6764, 2019 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31306022
14.
Understanding the autocatalytic process of pro-kumamolisin activation from molecular dynamics and quantum mechanical/molecular mechanical (QM/MM) free-energy simulations.
Chemistry
; 19(33): 10849-52, 2013 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23821374
15.
Kinetic characterization of cholinesterases and a therapeutically valuable cocaine hydrolase for their catalytic activities against heroin and its metabolite 6-monoacetylmorphine.
Chem Biol Interact
; 293: 107-114, 2018 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30080993
16.
QM/MM free energy Simulations of an efficient Gluten Hydrolase (Kuma030) Implicate for a Reactant-State Based Protein-Design Strategy for General Acid/Base Catalysis.
Sci Rep
; 8(1): 7042, 2018 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29728674
17.
Unexpected Reaction Pathway for butyrylcholinesterase-catalyzed inactivation of "hunger hormone" ghrelin.
Sci Rep
; 6: 22322, 2016 Feb 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26922910
18.
Potential anti-obesity effects of a long-acting cocaine hydrolase.
Chem Biol Interact
; 259(Pt B): 99-103, 2016 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27163854
19.
Role of Histidine 547 of Human Dopamine Transporter in Molecular Interaction with HIV-1 Tat and Dopamine Uptake.
Sci Rep
; 6: 27314, 2016 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27250920
20.
PPCM: Combing Multiple Classifiers to Improve Protein-Protein Interaction Prediction.
Int J Genomics
; 2015: 608042, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26539460