Detalhe da pesquisa
1.
Diff-AMP: tailored designed antimicrobial peptide framework with all-in-one generation, identification, prediction and optimization.
Brief Bioinform
; 25(2)2024 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38446739
2.
Improving drug response prediction via integrating gene relationships with deep learning.
Brief Bioinform
; 25(3)2024 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38600666
3.
Predicting molecular properties based on the interpretable graph neural network with multistep focus mechanism.
Brief Bioinform
; 24(1)2023 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36526280
4.
GCFMCL: predicting miRNA-drug sensitivity using graph collaborative filtering and multi-view contrastive learning.
Brief Bioinform
; 24(4)2023 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37427977
5.
Improving drug-target affinity prediction via feature fusion and knowledge distillation.
Brief Bioinform
; 24(3)2023 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37099690
6.
mRNA-CLA: An interpretable deep learning approach for predicting mRNA subcellular localization.
Methods
; 227: 17-26, 2024 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-38705502
7.
An analgesic peptide H-20 attenuates chronic pain via the PD-1 pathway with few adverse effects.
Proc Natl Acad Sci U S A
; 119(31): e2204114119, 2022 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35878019
8.
Development of a Decafluorobiphenyl Cyclized Peptide Targeting the NEMO-IKKα/ß Interaction that Enhances Cell Penetration and Attenuates Lipopolysaccharide-Induced Acute Lung Injury.
Bioconjug Chem
; 35(5): 638-652, 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38669628
9.
An Effective Plant Small Secretory Peptide Recognition Model Based on Feature Correction Strategy.
J Chem Inf Model
; 64(7): 2798-2806, 2024 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37643082
10.
ML-NPI: Predicting Interactions between Noncoding RNA and Protein Based on Meta-Learning in a Large-Scale Dynamic Graph.
J Chem Inf Model
; 64(7): 2912-2920, 2024 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37920888
11.
Genetic Algorithm-Based Receptor Ligand: A Genetic Algorithm-Guided Generative Model to Boost the Novelty and Drug-Likeness of Molecules in a Sampling Chemical Space.
J Chem Inf Model
; 64(4): 1213-1228, 2024 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38302422
12.
Discovery of a potent and selective PARP1 degrader promoting cell cycle arrest via intercepting CDC25C-CDK1 axis for treating triple-negative breast cancer.
Bioorg Chem
; 142: 106952, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37952486
13.
StableDNAm: towards a stable and efficient model for predicting DNA methylation based on adaptive feature correction learning.
BMC Genomics
; 24(1): 742, 2023 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38053026
14.
MolAICal: a soft tool for 3D drug design of protein targets by artificial intelligence and classical algorithm.
Brief Bioinform
; 22(3)2021 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32778891
15.
An effective self-supervised framework for learning expressive molecular global representations to drug discovery.
Brief Bioinform
; 22(6)2021 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33940598
16.
TrimNet: learning molecular representation from triplet messages for biomedicine.
Brief Bioinform
; 22(4)2021 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33147620
17.
Can machine learning consistently improve the scoring power of classical scoring functions? Insights into the role of machine learning in scoring functions.
Brief Bioinform
; 22(1): 497-514, 2021 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31982914
18.
Accuracy or novelty: what can we gain from target-specific machine-learning-based scoring functions in virtual screening?
Brief Bioinform
; 22(5)2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33418562
19.
Gauge Invariance of Non-Abelian Field Strength Correlators: The Axial Gauge Puzzle.
Phys Rev Lett
; 130(5): 052302, 2023 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36800457
20.
Upgrade of chrysomycin A as a novel topoisomerase II inhibitor to curb KRAS-mutant lung adenocarcinoma progression.
Pharmacol Res
; 187: 106565, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36414124