Detalhe da pesquisa
1.
Quercetagitrin Inhibits Tau Accumulation and Reverses Neuroinflammation and Cognitive Deficits in P301S-Tau Transgenic Mice.
Molecules
; 28(9)2023 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37175376
2.
Tau acetylates and stabilizes ß-catenin thereby promoting cell survival.
EMBO Rep
; 21(3): e48328, 2020 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31930681
3.
Tau accumulation triggers STAT1-dependent memory deficits by suppressing NMDA receptor expression.
EMBO Rep
; 20(6)2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31085626
4.
Tau accumulation induces synaptic impairment and memory deficit by calcineurin-mediated inactivation of nuclear CaMKIV/CREB signaling.
Proc Natl Acad Sci U S A
; 113(26): E3773-81, 2016 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27298345
5.
New Anti-Inflammatory Aporphine and Lignan Derivatives from the Root Wood of Hernandia nymphaeifolia.
Molecules
; 23(9)2018 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30205430
6.
Targeting tau in Alzheimer's disease: from mechanisms to clinical therapy.
Neural Regen Res
; 19(7): 1489-1498, 2024 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38051891
7.
HDAC7 Activates IKK/NF-κB Signaling to Regulate Astrocyte-Mediated Inflammation.
Mol Neurobiol
; 59(10): 6141-6157, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35871708
8.
A novel small-molecule PROTAC selectively promotes tau clearance to improve cognitive functions in Alzheimer-like models.
Theranostics
; 11(11): 5279-5295, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33859747
9.
Medial septum tau accumulation induces spatial memory deficit via disrupting medial septum-hippocampus cholinergic pathway.
Clin Transl Med
; 11(6): e428, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34185417
10.
Periphery Biomarkers for Objective Diagnosis of Cognitive Decline in Type 2 Diabetes Patients.
Front Cell Dev Biol
; 9: 752753, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34746146
11.
Peripheral inflammation promotes brain tau transmission via disrupting blood-brain barrier.
Biosci Rep
; 40(2)2020 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32043530
12.
Tau inhibits PKA by nuclear proteasome-dependent PKAR2α elevation with suppressed CREB/GluA1 phosphorylation.
Aging Cell
; 19(1): e13055, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31668016
13.
Tau-induced upregulation of C/EBPß-TRPC1-SOCE signaling aggravates tauopathies: A vicious cycle in Alzheimer neurodegeneration.
Aging Cell
; 19(9): e13209, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32815315
14.
Co-Expression of Three Wild-Type 3R-Tau Isoforms Induces Memory Deficit via Oxidation-Related DNA Damage and Cell Death: A Promising Model for Tauopathies.
J Alzheimers Dis
; 73(3): 1105-1123, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31884489
15.
Tau-Induced Ca2+/Calmodulin-Dependent Protein Kinase-IV Activation Aggravates Nuclear Tau Hyperphosphorylation.
Neurosci Bull
; 34(2): 261-269, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28646348
16.
TRPC1 Null Exacerbates Memory Deficit and Apoptosis Induced by Amyloid-ß.
J Alzheimers Dis
; 63(2): 761-772, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29660945
17.
Accumulation of human full-length tau induces degradation of nicotinic acetylcholine receptor α4 via activating calpain-2.
Sci Rep
; 6: 27283, 2016 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27277673