Inkjet-Printed Salt-Encapsulated Quantum Dot Film for UV-Based RGB Color-Converted Micro-Light Emitting Diode Displays.

A promising method has been demonstrated to fabricate quantum dot (QD)-converted full-color micro-light emitting diodes (LEDs) by inkjet printing (IJP) instead of the mass transfer of three red-green-blue (RGB) color chips. By introducing an additional medium, that is, NaCl into a formulated ink, QD deposition is manipulated by the NaCl-QD adhesive force and the capillary flow inside the liquid drop via varying the substrate hydrophobicity, which enabled spontaneous self-encapsulation of QDs in a single NaCl crystal. An RGB QD@NaCl array with a small pixel size and uniform size distribution (diameter = 3.74 ± 0.5 µm) is obtained in the IJP process, which demonstrated a full-color micro-LED display with a color gamut of approximately 110% of the National Television System Committee (NTSC) standard.

Investigation of Luminescence Enhancement and Decay of QD-LEDs: Interface Reactions between QDs and Atmospheres.

We investigated the current unsolved problem of short-term enhancement and long-term decay of the luminescence intensity of quantum dots (QDs)-based light-emitting diodes (LEDs) in applications for lighting and displays, and proved that the interface interaction between the QD surface and atmospheres plays a key role in the QD-LED operation process. It is suggested that the initial luminescence enhancement of QD-LEDs would be caused by the QD surface-adsorbed species, such as ligands and gas molecules, rather than QDs themselves, whereas the luminescence decay is correlated to the interface reactions between QDs and photo-generated reactive oxygen species, which leads to formations of sulfate, hydroxide, and oxide compounds after QDs are illuminated by 450 nm blue light in oxygen and water environments according to surface analysis and theoretic thermodynamic calculations. It was also found that involvement of water in the QD-LED operation can cause crystal merging of QDs possibly because of the surface sulfates in the presence of water.

Detection of the inferred interaction network in hepatocellular carcinoma from EHCO (Encyclopedia of Hepatocellular Carcinoma genes Online).

BACKGROUND: The significant advances in microarray and proteomics analyses have resulted in an exponential increase in potential new targets and have promised to shed light on the identification of disease markers and cellular pathways. We aim to collect and decipher the HCC-related genes at the systems level. RESULTS: Here, we build an integrative platform, the Encyclopedia of Hepatocellular Carcinoma genes Online, dubbed EHCO http://ehco.iis.sinica.edu.tw, to systematically collect, organize and compare the pileup of unsorted HCC-related studies by using natural language processing and softbots. Among the eight gene set collections, ranging across PubMed, SAGE, microarray, and proteomics data, there are 2,906 genes in total; however, more than 77% genes are only included once, suggesting that tremendous efforts need to be exerted to characterize the relationship between HCC and these genes. Of these HCC inventories, protein binding represents the largest proportion (~25%) from Gene Ontology analysis. In fact, many differentially expressed gene sets in EHCO could form interaction networks (e.g. HBV-associated HCC network) by using available human protein-protein interaction datasets. To further highlight the potential new targets in the inferred network from EHCO, we combine comparative genomics and interactomics approaches to analyze 120 evolutionary conserved and overexpressed genes in HCC. 47 out of 120 queries can form a highly interactive network with 18 queries serving as hubs. CONCLUSION: This architectural map may represent the first step toward the attempt to decipher the hepatocarcinogenesis at the systems level. Targeting hubs and/or disruption of the network formation might reveal novel strategy for HCC treatment.

Wide gamut white light emitting diodes using quantum dot-silicone film protected by an atomic layer deposited TiO2 barrier.

Wide gamut light emitting diodes using quantum dot-silicone film protected by atomic layer deposited TiO2 film were demonstrated. The core/shell QDs with multi-emission peaks were synthesised by a one-pot approach, in which the emission wavelength and colour composition were in situ adjusted during the synthetic process.

Three-dimensional reconstruction of brain-wide wiring networks in Drosophila at single-cell resolution.

BACKGROUND: Animal behavior is governed by the activity of interconnected brain circuits. Comprehensive brain wiring maps are thus needed in order to formulate hypotheses about information flow and also to guide genetic manipulations aimed at understanding how genes and circuits orchestrate complex behaviors. RESULTS: To assemble this map, we deconstructed the adult Drosophila brain into approximately 16,000 single neurons and reconstructed them into a common standardized framework to produce a virtual fly brain. We have constructed a mesoscopic map and found that it consists of 41 local processing units (LPUs), six hubs, and 58 tracts covering the whole Drosophila brain. Despite individual local variation, the architecture of the Drosophila brain shows invariance for both the aggregation of local neurons (LNs) within specific LPUs and for the connectivity of projection neurons (PNs) between the same set of LPUs. An open-access image database, named FlyCircuit, has been constructed for online data archiving, mining, analysis, and three-dimensional visualization of all single neurons, brain-wide LPUs, their wiring diagrams, and neural tracts. CONCLUSION: We found that the Drosophila brain is assembled from families of multiple LPUs and their interconnections. This provides an essential first step in the analysis of information processing within and between neurons in a complete brain.