Detalhe da pesquisa
1.
Base editing of haematopoietic stem cells rescues sickle cell disease in mice.
Nature
; 595(7866): 295-302, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34079130
2.
Editing human hematopoietic stem cells: advances and challenges.
Cytotherapy
; 25(3): 261-269, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36123234
3.
Bone-marrow-homing lipid nanoparticles for genome editing in diseased and malignant haematopoietic stem cells.
Nat Nanotechnol
; 2024 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38783058
4.
An RPS19-edited model for Diamond-Blackfan anemia reveals TP53-dependent impairment of hematopoietic stem cell activity.
JCI Insight
; 8(1)2023 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36413407
5.
Multiplex Base Editing to Protect from CD33-Directed Therapy: Implications for Immune and Gene Therapy.
bioRxiv
; 2023 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36865281
6.
Ex vivo prime editing of patient haematopoietic stem cells rescues sickle-cell disease phenotypes after engraftment in mice.
Nat Biomed Eng
; 7(5): 616-628, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37069266
7.
Potent and uniform fetal hemoglobin induction via base editing.
Nat Genet
; 55(7): 1210-1220, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37400614